end point


Also found in: Dictionary, Thesaurus, Legal, Financial, Acronyms, Encyclopedia, Wikipedia.

end point

the completion of a reaction.

end point

1 (in chemistry) the point at which the condition of equivalence is reached during a titration. This may be indicated by reaching a maximum value in the slope of a titration curve, for example.
2 the point or time at which an activity is finished.
3 the point at which a chemical indicator changes color, for example, in an acid-base titration.

end point

Outcome, see there Clinical trials A measured outcome that marks the closure of a particular clinical question; EPs may be true–eg, reduction of mortality, prolongation of life, or surrogate–eg, lowering of BP, ↓ arrhythmias Lab medicine Any final point in a reaction or process, at which time the results are analyzed or interpreted.

end point

(end poynt)
Overused jargon for termination or conclusion.
References in periodicals archive ?
The tests are also useful in that the end points evaluated correspond to the biological processes in humans that one wishes to protect (e.
The role of biomarkers in drug discovery: overview of what defines a biomarker and how biomarkers can act as surrogate end points in clinical trials.
These modifications allow the incorporation of standard microarray data in conjunction with conventional toxicological end points (e.
The disadvantages of the fish GRA include the absence of any published data on gonadal recrudescence in OECD test species; unlike other approaches that seek to enhance existing regulatory test guidelines for testing endocrine disruptors (28), the GRA has no clear link to an existing regulatory protocol, and the practical use of end points such as gamete quality and fecundity in such a screening assay incurs a high degree of interindividual variability because cyprinid fish have widely variable fecundity between breeding pairs, even within control populations.
Biomarkers of effect may be either early events on the direct pathway to disease or toxic end points or predictors of disease or toxicity outside the direct pathway, i.
And though one might say that is the real end point of all their efforts, Shenoy thinks they can do better.
Two of these standards efforts, in particular, are designed to help reduce latency at the end points by lessening the impact of the TCP/IP transmission protocol that sits atop Ethernet.
In contrast, for in-office measurements at baseline, every 10-mm Hg increase in systolic blood pressure raised the risk of the combined end points by 18%, and each 10-mm Hg increase in diastolic pressure raised the risk by 11%.
Although, on the face of it, this may seem like a reasonable way to inject rigor into a complicated process, placing overly strict limitations on interpretation of gene expression data ensures that only the end points now assessed by traditional toxicology tests will be the end points considered in the future.
This system allows researchers to investigate questions about mechanisms by measuring functional end points of estrogen action, such as prolactin secretion, which increases upon exposure to estrogen.
Specific end points recommended for tracking include asthma and chronic respiratory diseases, and chronic neurodegenerative diseases such as multiple sclerosis.
The studies are designed to capture changes in viral burden, T-cell counts and clinical end points.