The primary end points
and the secondary end point
were no significant differences between two groups with the in-hospital and long-term follow-up.
Lower the machine needle down into the fabric precisely at the dart end point
, just one thread away from the fold (8).
However, although statistical analysis of the appropriate data can eliminate mutual confounding, care is required to address the most sensitive end points
that may be sensitive to risk and not benefit.
The patient is not in a position to know in advance what welfare or disability is or, in other words, what the end point
of rehabilitation could be.
They were randomized to one of two open-label antihypertensive treatment strategies featuring blinded end point
assessment: a [beta]-blocker with added diuretic as needed, or a calcium channel blocker plus an angiotensin converting enzyme inhibitor.
This acts to minimise the errors associated with the traditional indicators, which mask or blur the end point
due to the samples colouration, so accurate and reproducible analysis is assured.
Primary end point
results observed from the 100% patient enrollment point in the study's open-label phase are consistent with those observed at the 25% and 50% milestone assessments.
"This approval is the first to use the end point
of metastasis-free survival," Richard Pazdur, M.D., director of the FDA's Oncology Center of Excellence and acting director of the Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research, said in a statement.
Vaughan Clift, Ampio's Chief Regulatory Officer (CRO), has completed analysis of the primary end point
in the Optina clinical trial for DME diabetic macular oedema conducted at St Michael Diabetes Hospital in Toronto Canada.
M2 PHARMA-June 11, 2012-Ampio Pharmaceuticals Inc's CRO completes analysis of primary end point
in Optina(tm) clinical trial for Diabetic Macular Edema(C)2012 M2 COMMUNICATIONS
In the first trial (Trial 303), 21.2% and 19.4% of patients on the 145-mcgand 290-mcg doses, respectively, achieved the study's primary end point
of three or more complete spontaneous bowel movements (CSBMs) per week plus an increase of one or more CSBMs per week over baseline during at least 9 of the 12 study weeks.