The mean LV End Diastolic Volume
measured with MRI was statistically significant (<0.001) when compared with mean LV End Diastolic Volume
measured by echocardiography.
On comparison of the baseline parameters to second follow-up, the conventional echocardiographic parameters representing systolic and diastolic function of LV showed statistically significant increase in End Diastolic Volume
(EDV) mL (58.86 [+ or -] 13.26 vs 67.43 [+ or -] 13.74, p < 0.037) (Table-4).
Percent Stretch from Baseline with an Infusion Rate of 500 mL [min.sup.-1] at Varying Heart Rates and Cardiac Outputs HR CO EDV EDV during (bpm) (mL [min.sup.-1]) (mL) Infusion (mL) % Stretch 60 2000 55.6 63.9 4.8 60 4000 111.1 119.4 2.4 60 6000 166.7 175.0 1.6 60 8000 222.2 230.5 1.2 90 2000 37.0 42.6 4.8 90 4000 74.1 79.7 2.4 90 6000 111.1 116.7 1.6 90 8000 148.1 153.7 1.2 120 2000 27.8 31.9 4.8 120 4000 55.6 59.8 2.4 120 6000 83.3 87.5 1.6 120 8000 111.1 115.3 1.2 HR: heart rate; CO: cardiac output; EDV: end diastolic volume
The left ventricle was severely dilated with a left ventricular end diastolic volume
index of 104 ml/[m.sup.2] (normal < 76 ml/[m.sup.2]) with mild concentric wall thickening with a maximum wall thickness of 16 mm.
This allows the increased venous return to be accommodated without relevant changes in left ventricular end diastolic volume
(either it is increased or may remain constant).
The results about standard cardiac MR parameters on morphology (LV end diastolic volume
, end systolic volume, and mass) and systolic function have been published in our previous paper .
A positive trend was seen across all treatment groups, and the primary endpoint was met (p=0.015) for a subset representing 60 percent of the population of the CHART-1 study (baseline End Diastolic Volume
End Systolic Volume Index, ESV-I (EsV/BSA in [m.sup.2]) and End Diastolic Volume
Index, EDV-I (EDV/BSA in [m.sup.2]) calculated from left apical 4-chamber view were 106.05 ml/[m.sup.2] and 143.6 ml/[m.sup.2] respectively.
WJMSs are also naturally chemoattracted to cardiac tissues, and as a result they are highly specific to cardiac tissues.5 Previous studies have shown that the transfer of bone marrow mononuclear cells (BMMCs) had no significant impact on left ventricular end diastolic volume
(LVEDV), suggesting that BMMCs may have a limited effect on LV remodeling after acute MI.6
In this follow-up, CO, left ventricular end diastolic volume
, and radial movement of myofibrils did not change significantly.
Perhonen and colleagues used magnetic resonance imaging (MRI) to measure the mass of the left and right ventricular myocardial mass, end diastolic volume
of the left ventricle in 3 healthy men before and after 2-, 6-, and 12-weeks of bed rest in a horizontal position, and in 8 astronauts before and after 10-day space flight.
In this group of patients, volume expansion may improve VR and left ventricular end diastolic volume