Recent research reports depict that Geminiviruses possess single stranded DNA (ssDNA) molecules (~2500 to ~3100 nucleotides) encapsidated
in twinned icosahedral capsid, with circular monopartite or bipartite genomes but can encode only few genes and its replication mostly depend on host plant replication machinery.
The polio virion consists of a single-stranded positive sense RNA molecule encapsidated
by an icosahedral capsid which is self-possessed of four proteins VP1, VP2, VP3 and VP4.
4 kb encapsidated
inexuous lamentous particles, which contains ve open reading frames (ORFs).
20,21] If IL-12 expressing plasmid DNA could be encapsidated
in VLP, this pseudovirion could be an ideal biochemical agent to be used as a therapeutic agent for HPV infection and cervical cancer.
A further variation on this can exist in the form of assay-specific target nucleic acids (not complete organisms), artificially encapsidated
in something similar to a live organism.
The RNA form of the genome is encapsidated
together with the reverse transcriptase, and reverse transcription occurs within the cytoplasm.
Geminiviruses are small plant viruses characterized by a covalently closed circular single stranded (ss) DNA encapsidated
in twined (geminate) particles.
HAdVs are nonenveloped, linear double-stranded DNA viruses encapsidated
within a protein shell and have been categorized into 6 species (A-F) that contain 51 immunologically distinct serotypes (3).
The lead clinical candidate is a new class of agent containing three separate RNAi elements, simultaneously targeting three different sites of the Hepatitis C virus, and encapsidated
in an adeno-associated virus (AAV) protein coat.
In another aspect an adenovirus based helper construct which by its size is incapable of being encapsidated
HIV RNA control consisted of a consensus 172-base portion of the gag sequence for subtype B viruses encompassing the target amplification region for the Amplicor HIV-1 Monitor assay.
University of Alabama at Birmingham (Birmingham, AL) has patented a method of encapsidating a recombinant poliovirus nucleic acid to obtain a yield of encapsidated
viruses which substantially comprises encapsidated
recombinant poliovirus nucleic acid.