The results obtained thus demonstrate the usefulness of resolution of racemates and
enantiomerically enriched compounds in drug development of antimicrobial agents of coordinated compounds.
All naturally-occurring proteins are
enantiomerically pure because the amino acid building blocks that comprise proteins exist as single enantiomers.
They were able to introduce a chiral twist into these materials by inserting an
enantiomerically pure (one-handed) chiral monomer, such as indane bisphenol (IBP) or spirobiindane (SBI), into the polymer backbone.
Industrial chemists have also recruited legions of microorganisms and their enzymes to convert raw materials into
enantiomerically pure products.
Our further synthetic effort was focused on structural modifications of compound 3, including their
enantiomerically enriched forms (Scheme 3).
As is well known, discovery of the existence of enantiomeric isomers of organic compounds as well as their isolation as
enantiomerically pure isomers with the use of tweezers under microscope were performed for the preparation of
enantiomerically pure D-(-)- and L-(+)-tartaric acids as early as the mid-nineteenth century by L.
Yus, "Microwave-assisted solvent-free synthesis of
enantiomerically pure N-(tert-Butylsulfinyl)imines," Journal of Organic Chemistry, vol.
Preparation of
enantiomerically pure yaminobutyric acid and succinic acid derivatives," Helvetica Chimica Acta, vol.
Chiral epoxides are very important building blocks for the synthesis of
enantiomerically pure molecules of biologically active compounds and pharmaceuticals [1-3].
Thus, new methods for obtaining optically active sulfoxides are required for the synthesis of
enantiomerically enriched compounds.
This assay uses pseudo-prochiral (H5, D5) malonate diesters, which need only be
enantiomerically enriched, which is hydrolyzed under a variety of conditions and monitored by LDI-TOF or ESI-MS.
The direct synthesis of three
enantiomerically pure diastereomers of a 1-ferrroceylalkylamine from 1-(-)-menthone and the up-down-stereoisomerism of ferrocene derivatives.
