All naturally-occurring proteins are enantiomerically
pure because the amino acid building blocks that comprise proteins exist as single enantiomers.
They were able to introduce a chiral twist into these materials by inserting an enantiomerically
pure (one-handed) chiral monomer, such as indane bisphenol (IBP) or spirobiindane (SBI), into the polymer backbone.
Industrial chemists have also recruited legions of microorganisms and their enzymes to convert raw materials into enantiomerically
The stereochemical purity of the HCDA, (R)-MTP chloride, was determined by derivatization of enantiomerically
pure (+)-(1S,2S)-pseudoephedrine and examination of the diastereomeric composition of the derivatives, using the GC methodology.
Recent Advances in the Synthesis of Enantiomerically
Starting from enantiomerically
resolved trans-1,2-cyclohexanediamine, we initially targeted tridentate, C2-symmetric NHC-ligand precursors with two back-bonding hydroxy groups which are available via reductive amination and subsequent ring closing reaction with triethyl-orthoformate.
We have found that Sharpless-Katsuki complex is able to oxidize different cyclobutanones resulting in enantiomerically
Feringa has made efficient use of 5-menthyl-oxy-2(5H)-furanones to provide enantiomerically
pure synthons through "crystallization induced epimerization".
Used to resolve chiral compounds from racemic mixtures into pure enantiomers, SMB capability is one of the fastest methods to obtain enantiomerically
pure drugs, increasingly important as the demand for single-enantiomer drugs continues to grow.
2] or ROOH Many of these reactions, especially epoxidation of alkenes, can lead to enantiomerically
enriched chiral products.
N,N'-alkyl-R,R-tartramides have been used as enantiomerically
pure chiral auxiliaries in different catalysts [5-7].