93) The issues in the salt cases have important similarities to the enantiomer
2009) Chiral polymers for resolution of enantiomers
The transmembrane pores having relatively small diameter might be responsible for the selective separation of enantiomers
A combination of methanol/acetonitrile/water in the mobile phase is mandatory for separation of HBCD enantiomers
Table 2 Effects of GBE and bilohalide on plasma concentration of warfarin and 7-hydroxywarfarin enantiomers
in mice given warfarin racemate.
A representative chromatogram showing resolution of derivatives of enantiomers
is shown in Fig-2.
Although a court must not declare that a prima facie case of obviousness exists for an enantiomer
over its prior art racemate in the absence of the Graham factual inquiries, (132) the structural similarities between a single enantiomer
and its racemate are usually sufficient to establish a prima facie case.
75) The five methods of separating enantiomers
were well-known, but the PHOSITA would have no knowledge of the relative advantage of the d-enantiomer
But in December 2006 an appeals court found that the so-called 995 enantiomer
patent had a technical defect in that one claim Within it contained an improper cross-reference to another claim in the patent.
Lundbeck A/S v Generics (UK) Limited & Ors, the English Court of Appeal reversed in part the decision of the Patents Court and in so doing upheld broad product claim protection for escitalopram, the (+) enantiomer
of the racemate citalopram, that is responsible for the SSRI activity of citalopram.
DIO-902 (levdexketoconazole) is an oral, single enantiomer
of ketoconazole that is a novel cortisol synthesis inhibitor in development for type 2 diabetes mellitus and diabetic nephropathy.
, trade name Amplixa, has gotten the green light from the Food and Drug Administration for accelerated development on the strength of the reassuring safety profile established over many years by its racemic relative, mecamylamine, Dr.