empty sella syndrome


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empty sella syndrome

 
a syndrome diagnosed radiologically in which the diaphragm of the sella turcica is vestigial, the sella turcica forms an extension of the subarachnoid space and is filled with cerebrospinal fluid, and the pituitary fossa appears to be empty, although the pituitary gland is present in a flattened form.

empty sella syndrome

Etymology: AS, oemettig, unoccupied; L, sella, saddle
an abnormal enlargement of the sella turcica filled with cerebrospinal fluid. The pituitary gland may be smaller than normal and flattened, or it may be absent. Signs and symptoms of hormonal imbalance (for example, hypopituitarism) may be present, as may headache, but some patients are asymptomatic. The diagnosis may be made by computed axial tomography scan, skull radiographic study, or pneumoencephalography.
The finding of a moderately enlarged sella turcica, due to a partial/complete absence of the sellar diaphragm. ESS is an anatomic state characterised by an invagination of the arachnoid membrane space into the pituitary fossa, resulting in compression of the pituitary against the floor and posterior wall of the sella, by the extended suprasellar cisterns and expanded sella. It may be accompanied by pituitary hypofunction, although TSH, gonadotropin, and prolactin levels may be decreased and/or accompanied by diabetes insipidus

empty sella syndrome

Empty sella turcica, intrasellar arachnocele Neuroradiology The finding of a moderately enlarged sella turcica, due to a partial/complete absence of sellar diaphragm; it is most common in obese, middle-aged ♀; compression of hypophysis against the floor and posterior wall of the sella, by the extended suprasellar cisterns may be accompanied by pituitary hypofunction, although TSH, gonadotropin, and prolactin levels may be ↓ and/or accompanied by diabetes insipidus Clinical Vague headaches, systemic HTN, pseudotumor cerebri; if secondary, CSF rhinorrhea, but may be asymptomatic

empty sella syndrome

The radiological appearance suggesting that the hollow on top of the SPHENOID bone, the sella turcica (Turkish saddle), which normally contains the PITUITARY GLAND, is enlarged and empty. The appearance is often associated with complete normality but may indicate a pituitary tumour, atrophy of the pituitary gland, harmless herniation of the arachnoid layer of the meninges into the sella, or BENIGN INTRACRANIAL HYPERTENSION.
References in periodicals archive ?
Men with empty sella syndrome had significantly higher prolactin (PRL), compared with men who had normal MRIs (21.
Men with empty sella syndrome had significantly higher prolactin, compared with men who had normal MRIs (21.
4,5,6,7) Empty sella syndrome, panhypopituitarism, diabetes insipidus, short stature and obesity in a 18 months old baby probably secondary to obstetrics insult was also reported.
12(7%) cases of complete/partial empty sella syndrome were seen.
Pathologic hyperprolactinaemia may be due Microadenoma, Macroadenoma and empty sella syndrome (partial or complete).
MRI findings were grouped as Normal, Microadenomas, Macroadenomas, Complete empty sella syndrome and Partial empty sella syndrome.
3%) showed macro adenoma, 6 (7%) showed empty sella syndrome and 6 (7%) showed partially empty sella syndrome.
It develops from bilateral involvement of the uncrossed fibers at the chiasma such as bilateral internal carotid artery atherosclerosis or aneurysm, olfactory groove meningioma, empty sella syndrome, chronic raised intracranial pressure, and neurosyphilis affecting both optic nerves.
But it is doubtful that they would know diseases such as West Syndrome, Whipple's disease, Buerger's disease, yellow-nail syndrome, empty sella syndrome, or Job (as in the Old Testament) syndrome.
d/h Hypo pituitarism has varied etiology, most common being pituitary adenomas (Macro 75 % and others 20%), Sheehan syndrome, familial hypopituitarism, idiopathic, hypophysitis, empty sella syndrome, snake bite being other causes.
37, 8 Ectopic production Breastfeeding Breast stimulation Hypothyroidism Medications Empty sella syndrome Pituitary adenoma Autoimmune Chemotherapy Galactosemia Genetic 17-hydroxylase deficiency syndrome Idiopathic Mumps Pelvic radiation Chronic liver disease Chronic renal insufficiency Diabetes Immunodeficiency Inflammatory bowel disease Thyroid disease Severe depression or psychosocial stressors Acromegaly Androgen-secreting tumor (ovarian or adrenal) Cushing's disease Exogenous androgens Polycystic ovary syndrome Thyroid disease Asherman's syndrome Cervical stenosis TABLE 4: Causes of secondary amenorrhea in study group.