Conclusion: Frequency of VAP is quite high in our setup, identification of causative bacterial pathogens and their antibiotic susceptibility pattern will not only help in providing effective treatment to the patients but will also help in the formulation of antibiogram according to local resistance patterns for empirical therapy
and to reduce the morbidity and mortality.
The indications for colistin therapy were recorded as follows: empirical therapy
(if no evidence of an MDR or XDR Gram-negative organism was found prior to or during the course of treatment), directed therapy (infection with an MDR or XDR organism of known sensitivity) or salvage therapy (failure of an alternative treatment where colistin was used as escalation therapy).
Survival benefit of empirical therapy
for staphylococcus aureus bloodstream infections in infants.
9] Although empirical therapy
for EOS should be individualised per hospital or region, a widely accepted empirical regimen is a combination of ampicillin plus an aminoglycoside.
Knowledge of causative agents of pyogenic infection and their antibiotic sensitivity pattern is very essential for the judicial administration of empirical therapy
before culture result are available.
aureus]) and/or in children with a greater severity of illness, in whom potential resistance can limit clindamycin's utility as empirical therapy
," they added.
After the operation, piperacillin-tazobactam, teicoplanin and fluconazole were given as an empirical therapy
Oral ciprofloxacin 500 mg twice daily and metronidazole 500 mg 4 times daily were initiated as empirical therapy
The best cost/benefit empirical therapy
in children is still ceftriaxone/cefuroxime for parenteral therapy (2,4,8).
To understand resistance pattern of uropathogens which assist in choosing empirical therapy
for urinary tract infections (UTI).
Her general practitioner performed chest radiographs, which showed diffuse bilateral infiltrates in the middle and lower lung fields, but empirical therapy
for suspected atypical pneumonia with azithromycin was without benefit.
In conclusion, the risk stratification using the D-index was a useful tool to a more comprehensive antifungal strategy, resulting in reduction of empirical therapy
in low risk patients, and guiding an earlier start of antifungal agents in afebrile patients at high risk who presented an indirect sign of IMD.