levofloxacin, 500 mg daily, as
empirical therapy, then was admitted to the intensive care unit because he required non-invasive ventilation.
Empirical therapy with ceftriaxone 2 g was started.
Another choice is rifaximin (weak recommendation, moderate LOE), although one should exercise caution for
empirical therapy in regions in which being at high risk of invasive pathogens is anticipated.
[22] Periodic updated knowledge of local microbiological VAP data is useful for modification of old
empirical therapy of VAP in hospitals.
This is among the little mistakes medics in the field make in the name of pushing sales, putting the life of millions of people at the risk of antibiotic resistance.Pharmacists and clinicians should handle patients who prefer
empirical therapy as uninformed persons in drug pharmacokinetic and pharmacodynamic.
The aim of this study is to know the prevalence and drug resistance pattern of MRSA among various pus samples and to know the number of multidrug resistant (MDR) and extensively drug resistant (XDR) strains in order to utilize the information obtained for choosing
empirical therapy, to screen colonized patients or staff and formulate appropriate control measures.
Another objective was to discover the common causative agents of asymptomatic bacteriuria in our population so that appropriate
empirical therapy may be initiated even when test results are unavailable.
De-escalation of
empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock.
Consequently, CUP always has poor prognosis because such type of cases are commonly treated with non-selective
empirical therapy (1).
It has also served as a criterion for the immediate initiation of
empirical therapy in our patients.
Empirical therapy includes broad-spectrum antibiotics with an anaerobic activity and high blood-brain barrier penetration.
We investigated antimicrobial susceptibility and multidrug-resistance of the isolated Pseudomonas strains and evaluated appropriateness of the
empirical therapy in the ED.