QUEZALES UNTIDILY ACHROMIC FLEABANE FERMENTS (81) HAPHAZARD AQUILEGIA SUCCORING TAEKWONDO (77) SCOFFLAWS HYPEREMIA AMATIVELY HALAZONES (77) HAMADA EXEQUY MIZUNA PLEACH YESSES (76) SNIPPER NONHOME EIDOLIC ESERINE ZONATED EMETINE
RESECTS (75) HARIJAN ATOMIZE WASABIS EXIGENT DYNODES (74) PRELATE SEMILOG HEEZING ACTABLE WHIRLER SYNDETS (74) REPAST EXARCH DUNKER EVZONE FIESTA YAREST (73) The smallest size having a unique highest-scoring grid is 6x2; of the 72,093 6x2's, only one achieves the maximum score of 37.
28.7 [+ or -] 8.8 (Padmaja, R., et al, 2002)] (b) Emetine
hydrochloride (c) nd; 20.1 [+ or -] 0.2 (Wanyoike, G.N., et al., 2004) (b) Cyclophosphamide (c) nd;16.3 [+ or -] 6.0 (Moshi, M.J., et al, 2004) (b) nd: not determined; (a) [LC.sub.50] is the lethal concentration of extract at which 50% mortality (lethality) of brine shrimp nauplii was observed; (b) mentioned [LC.sub.50] values for Acorus calamus, piperine and reference standards (Emetine
HCl and Cyclophosphamide) have been taken from literature; (c) positive standards.
Production of the alkaloids emetine
and cephaeline in callus cultures of Cephaelis ipecacuanha.
Must be the massive doses of sulfa, emetine
, arsenic, 3,000,000 units of penicillin, and all the bismuth.
, the ingredient that triggers the vomit reflex, attaches to the heart muscle, where it can cause cardiac arrest.
Once the rate of protein synthesis (described above) was obtained, an inhibitor of protein synthesis (emetine
) was used.
Plants are reported to have antimicrobial agents such as emetine
quinine and berberine tannins terpenoids alkaloids and falvonoids (Marjorie 1999).
(6) Some significant examples from this group of natural products include the analgesic morphine from Papaver somniferum L., the anti-gout colchicine from Colchicum autumnale L., the emetic and antiamoebic emetine
from Cephaelis ipecacuanha (Brot.) A.
We took a two-fold approach in which the effect of high pC[O.sub.2] was first tested on the dark respiration of coral recruits exposed to emetine
to inhibit protein synthesis (Fenteany and Morse, 1993; Pace and Manahan, 2006).
The alkaloid emetine
as a promising agent for the induction and enhancement of drug-induced apoptosis in leukemia cells.
neumayeri were conducted by quantifying the difference in protein synthesis and oxygen consumption rates in the presence and absence of the inhibitors anisomycin and emetine
(Sigma Chemical Co.).
Success stories include the treatment of malaria and amoebiasis using the alkaloids, quinine and emetine
obtained from Cinchona and Cephalis, respectively; in more recent times, Artemisinin, a sesquiterpene lactone derived from the herb Artemisia annua has been an invaluable addition (Golenser et al.