emetine

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emetine

[em´ĕ-tēn]

an alkaloid derived from ipecac or produced synthetically; its hydrochloride salt is used as an antiamebic.

em·e·tine

(em'ĕ-tēn),

The principal alkaloid of ipecac, used as an emetic; its salts are used in amebiasis; available as the hydrochloride.

emetine

(ĕm′ĭ-tēn′)

A bitter-tasting crystalline alkaloid, C₂₉H₄₀N₂O₄, derived from ipecac root and used in the treatment of amebiasis and as an emetic.

em·e·tine

(em'ĕ-tēn)

The principal alkaloid of ipecachuana (q.v.); used as an emetic; its salts are used in amebiasis; available as the hydrochloride.

emetine

An alkaloid derived from ipecacuanha sometimes used in the treatment of AMOEBIASIS. It has now been largely replaced by the safer METRONIDAZOLE.

em·e·tine

(em'ĕ-tēn)

The principal alkaloid of ipecac, used as an emetic.

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28.7 [+ or -] 8.8 (Padmaja, R., et al, 2002)] (b) Emetine hydrochloride (c) nd; 20.1 [+ or -] 0.2 (Wanyoike, G.N., et al., 2004) (b) Cyclophosphamide (c) nd;16.3 [+ or -] 6.0 (Moshi, M.J., et al, 2004) (b) nd: not determined; (a) [LC.sub.50] is the lethal concentration of extract at which 50% mortality (lethality) of brine shrimp nauplii was observed; (b) mentioned [LC.sub.50] values for Acorus calamus, piperine and reference standards (Emetine HCl and Cyclophosphamide) have been taken from literature; (c) positive standards.

Cytotoxicity screening of selected Indian medicinal plants using brine-shrimp lethality bioassay

Production of the alkaloids emetine and cephaeline in callus cultures of Cephaelis ipecacuanha.

Micropropagacion de la planta medicinal psychotria acuminata (1/ 2/)

Must be the massive doses of sulfa, emetine, arsenic, 3,000,000 units of penicillin, and all the bismuth.

The mysterious death of Richard Wright; suspicious events raise questions about last days of novelist

Emetine, the ingredient that triggers the vomit reflex, attaches to the heart muscle, where it can cause cardiac arrest.

Ipecac can cause death, bulimics warned

Once the rate of protein synthesis (described above) was obtained, an inhibitor of protein synthesis (emetine) was used.

Metabolic cost of protein synthesis in larvae of the Pacific oyster (Crassostrea gigas) is fixed across genotype, phenotype, and environmental temperature

Plants are reported to have antimicrobial agents such as emetine quinine and berberine tannins terpenoids alkaloids and falvonoids (Marjorie 1999).

IN VITRO EFFICACY OF GARLIC GLYCYRRHIZA AND NEEM AGAINST LOCAL ISOLATES OF MYCOPLASMA GALLISEPTICUM

(6) Some significant examples from this group of natural products include the analgesic morphine from Papaver somniferum L., the anti-gout colchicine from Colchicum autumnale L., the emetic and antiamoebic emetine from Cephaelis ipecacuanha (Brot.) A.

Microbial production of isoquinoline alkaloids as plant secondary metabolites based on metabolic engineering research

We took a two-fold approach in which the effect of high pC[O.sub.2] was first tested on the dark respiration of coral recruits exposed to emetine to inhibit protein synthesis (Fenteany and Morse, 1993; Pace and Manahan, 2006).

Evidence that high pC[O.sub.2] affects protein metabolism in tropical reef corals

The alkaloid emetine as a promising agent for the induction and enhancement of drug-induced apoptosis in leukemia cells.

Synergism of three-drug combinations of sanguinarine and other plant secondary metabolites with digitonin and doxorubicin in multi-drug resistant cancer cells

neumayeri were conducted by quantifying the difference in protein synthesis and oxygen consumption rates in the presence and absence of the inhibitors anisomycin and emetine (Sigma Chemical Co.).

Cost of protein synthesis and energy allocation during development of Antarctic sea urchin embryos and larvae

Success stories include the treatment of malaria and amoebiasis using the alkaloids, quinine and emetine obtained from Cinchona and Cephalis, respectively; in more recent times, Artemisinin, a sesquiterpene lactone derived from the herb Artemisia annua has been an invaluable addition (Golenser et al.