embryotoxicity

embryotoxicity

 [em″bre-o-tok-sis´ĭ-te]
toxic effects on the embryo of a substance that crosses the placental barrier; see also embryolethality and teratogenesis. adj. adj embryotox´ic.

em·bry·o·tox·ic·i·ty

(em'brē-ō-tok-sis'i-tē),
Injury to the embryo, which may result in death, growth retardation, or abnormal development of a part that may affect either its structure or function.

embryotoxicity

/em·bryo·tox·ic·i·ty/ (em″bre-o-tok-sis´ĭ-te) toxic effects on the embryo of a substance that crosses the placental membrane.

embryotoxicity

Toxicology Adverse effects on the embryo due to a substance that enters the maternal system and crosses the placental barrier; the effects of the substance may be expressed as embryonic death  or abnormal development of one or more body systems, and can be deleterious to maternal health. Cf Fetotoxicity.

em·bry·o·tox·ic·i·ty

(em'brē-ō-tok-sis'i-tē)
Injury to the embryo, which may result in death or abnormal development of a part, owing to substances that enter the placental circulation.

embryotoxicity

toxic to embryos.
References in periodicals archive ?
Niapour, Study of embryotoxicity of Perovskia abrotanoides, an adulterant in folk medicine during organogenesis in mice, Journal of Ethnopharmacology, 117, 108 (2008).
Embryotoxicity of orally administered misoprostol to pregnant mice.
For example, thalidomide causes damage to the embryo when exposure occurs between days 20 and 36 after fertilization, which coincides with an important period of embryonic development; exposures before or after this period have not been found to cause embryotoxicity (Vargesson 2015).
On the other hand, favipiravir has a risk for teratogenicity and embryotoxicity.
Alternatively, angiogenesis is not as important in RIF as it is in RM and maternal immune-mediated embryotoxicity, possibly via activated NK cells (44) or raised Th1 type immunity (45) being a more important factor.
The chick embryotoxicity screening test (CHEST) In: Neubert D, Merker J, Kwasigroch, T.
2] on freshwater and marine bivalves, including immunotoxicity, genotoxicity to gametes, reduced fertilization, embryotoxicity, reduced larval metamorphosis, and reduced growth and survival of larvae and juveniles (Calabrese et al.
Embryotoxicity of benzalkonium chloride in vaginally treated rats.
2012; 2013) indicated that exposure of Pacific oyster (Crassostrea gigas) to environmentally relevant concentrations of metolachlor may induce spermiotoxicity and embryotoxicity, caused by DNA damage and changes in expression of several genes, especially in the early life stages.
Smith, "Pre-implantation embryotoxicity after mouse embryo exposition to reactive oxygen species," Biocell, vol.
Artesunate and artelinic acid: association of embryotoxicity, reticulocytopenia, and delayed stimulation of hematopoiesis in pregnant rats.
In chronic experiments the parameters of chronic toxicity and embryotoxicity of compounds in a single seeding of the parental generation (P) and the constant seeding of Daphnia in a number of generations (P-F1-F2-F3) were determined in terms of "survival" and "fertility".