embryonic stem cell


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Related to embryonic stem cell: Somatic Stem Cell

embryonic stem cell

totipotent cells composing the inner cell mass of the blastocyst.

embryonic stem cell

Abbreviation: ES cell
A cell from the inner cell mass of the blastocyst (the 3-5 day old mammalian embryo) that can give rise to all the somatic cells of the body. Embryonic stem cells can be maintained as pure stem cell cultures.
See: adult stem cell
See also: cell

embryonic stem cell (ESC)

1. A cell taken from an early embryo and intended for therapeutic application of its totipotential property.
2. A cell derived from an embryo resulting from a donated egg whose nucleus has been removed and replaces by a cell from a prospective patient. During pregnancy some ESCs pass across the placental barrier and enter the mothers bloodstream. There are suggestions that these stem cells may repair damaged maternal organs, including the brain. Cells can be derived from umbilical cord blood that appear to have most of the properties of ESCs.
References in periodicals archive ?
Shapiro et al., "Embryonic stem cell lines derived from human blastocysts," Science, vol.
When the researchers ground the cells up and compared the genetic bits with those in embryonic stem cells, they didn't see much of a difference.
"Many discoveries with other cell types, notably the so-called reprogrammed [induced Pluripotent Stem] cells, would not happen without ongoing research in human embryonic stem cells."
There is particular variation in the ethical values and hence the laws governing embryonic stem cell use and derivation.
"How many published successes in human application are there for embryonic stem cells? Exactly zero.
Embryonic stem cells were cultured in DMEM with a high glucose concentration and 15% fetal calf serum supplemented with [beta]-mercaptoethanol, non-essential amino acids, antibiotics and L-glutamine and without leukaemia inhibitory factor (LIF).
Thus, when compared to adult stem cell research, the risks of embryonic stem cell research were often overstated and even false.
Specifically, the partners have succeeded in inducing most of neural cell species including neurons and glia cells from mouse embryonic stem cells. This achievement will lead to applications in human embryonic stem cells, shedding light on pediatric cerebral palsy.
In fact, the NAS guidelines preclude only three research activities involving either human embryos or human embryonic stem cells: (1) the research use of human embryos beyond fourteen days (or the appearance of the primitive streak, if that comes first); (2) the creation of embryonic chimeras involving the transfer of human embryonic stem cells into nonhuman primate blastocysts or the transfer of any embryonic stem cells into human blastocysts; and (3) the breeding of any chimeras into which human embryonic stem cells have been transferred at any stage of development.
It was in response to the Korean scientific advances that the Japanese government narrowly approved embryonic stem cell research.
At least three other states have considered funding stem cell research on adult cells only, which some lawmakers view as a promising alternative to embryonic stem cell research--and one with fewer ethical pitfalls.
Ever since President Bush banned federal funding for research on new embryonic stem cell lines in 2001, Lanza had seen financial backers shrink away as religious activists gained ground in the media, attacking researchers doing his sort of work.