electrospray ionization mass spectrometry


Also found in: Acronyms.

electrospray ionization mass spectrometry

A method of mass spectrometry used to obtain the chemical analysis and weight of large molecules, especially proteins and peptides using a very small sample. The electrospray provides a charge on the molecules which are then injected into a mass spectrometer to determine the ratio of charge to molecular mass.
References in periodicals archive ?
Zare, "Identification of fleeting electrochemical reaction intermediates using desorption electrospray ionization mass spectrometry," Journal of the American Chemical Society, vol.
Simultaneous identification of mycobacterial isolates to the species level and determination of tuberculosis drug resistance by PCR followed by electrospray ionization mass spectrometry. J Clin Microbiol 2011;49:908-17.
Detection of heartworm infection in dogs via PCR amplification and electrospray ionization mass spectrometry of nucleic acid extracts from whole blood samples.
ramillorum, therefore extracts obtained from different plant parts were analyzed by electrospray ionization mass spectrometry (ESI-MS) in order to evidence the presence of these bioactive alkaloids.
Capillary electrophoresis method development, electropherograms, electrophoretic mobility values, ultraviolet-visible spectra, and electrospray ionization mass spectrometry data are reported.
The companies" work has already been incorporated into EPA Method 332.0, "Determination of Perchlorate in Drinking Water by Ion Chromatography with Suppressed Conductivity and Electrospray Ionization Mass Spectrometry," published earlier this year, addressing IC/MS and IC/MS/MS.
This lipid removal was confirmed by electrospray ionization mass spectrometry. The delipidated viruses appear to represent a promising approach to the development of a therapy to treat HIV infected patients.
Column chromatography was used to purify and isolate the product, which was characterized by 1H NMR and Electrospray Ionization Mass Spectrometry. Characterization procedures were consistent with macrocycle formation, but further conformation is still necessary.
Advances in structural and functional proteomics are described in a chapter where electrospray ionization mass spectrometry is showcased in studies of noncovalent protein complexes.
The final presentation of the first day dealt with the identification of polymer end groups from MALDI or electrospray ionization mass spectrometry and then using this information to deduce mechanistic details in order to improve synthetic routes and yields.
Schneider's research focuses on understanding the mechanisms involved in electrospray ionization mass spectrometry (ESI-MS).