electroporation therapy

A local treatment modality for malignancy which uses brief, high-intensity, pulsed electrical currents to enhance the uptake of cytotoxic drugs, vaccines, and genes into cells by producing a transient increase in cell wall permeability

electroporation therapy

Therapeutics A form of drug delivery that generates electrical pulses via an electrode placed in a tumor to enhance the ability of a chemotherapeutic–eg, bleomycin to enter tumor cells involves using electric fields to open pores in human cells to allow easier and more efficient entrance of beneficial pharmaceutical products or genes. See Drug delivery, Iontophoresis.

e·lec·tro·po·ra·tion ther·a·py

(EPT) (ĕ-lek'trō-pōr-ā'shŭn thār'ă-pē)
Investigational therapy involving use of electric fields to open pores in human cells; provides for easier and more efficient entry of genes or pharmaceutical products.
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References in periodicals archive ?
(8) has successfully studied the effects of metallic brachytherapy implants on electroporation therapy based on this vegetal model.
The interaction between irreversible electroporation therapy (IRE) and embolization material using a validated vegetal model: an experimental study.
Nanda, "Electroporation therapy: a new approach for the treatment of head and neck cancer," IEEE Transactions on bio-Medical Engineering, vol.
Cancer immunotherapies company OncoSec Medical (OTCQB:ONCS) said on Tuesday that the US Patent and Trademark Office (USPTO) has approved claims covering a method of treating cancerous tumors with plasmid-encoded IL-15 and electroporation therapy to the tumor having a field strength of at least 700 V/cm.
According to the company, the new allowed patent application joins the patent US 8,026,223, which claims a method of treating cancerous tumors with plasmid-encoded IL-12 and electroporation therapy to the tumor; and patent US 8,802,643, which claims a method of treating cancerous tumors with plasmid-encoded B7-1, a peripheral membrane protein found on antigen-presenting cells (APCs) and electroporation therapy to the tumor, both of which have a field strength of at least 700 V/cm.
The Tweezertrodes can be used to reproduce applications requiring the caliper electrodes, including gene therapy, transdermal drug delivery and electroporation therapy. BTX www.btxonline.com, 800-272-2775
Previously performed studies, including Phase II results unveiled in 2001, have indicated that the electroporation therapy "eliminates the need for surgical removal of tumors," Genetronics President and CEO Avtar Dhillon asserted last month at the Wells Fargo Securities Healthcare Conference.
Genetronics Biomedical is a late stage biomedical company focused on building an oncology franchise based on its proprietary electroporation therapy. The therapy targets a significant unmet clinical need: the selective killing of cancer cells and local ablation of solid tumors while preserving healthy tissue.
Genetronics is a late stage biomedical company focused on building an oncology franchise based on its proprietary electroporation therapy (EPT).
Genetronics is a leader in electroporation therapy with over 240 patents issued, allowed, or pending.