dense-core granule

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dense-core granule

A round structure—“black” inside, “lighter” near the granule’s membrane—seen by electron microscopy which contains chromogranin and other proteins in various configurations. Dense-core granules serve as ultrastructural evidence of neuroendocrine differentiation.
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References in periodicals archive ?
gondii tachyzoites can cause marked decrease in rhoptries, disappearance of golgi complex and mitochondria, decrease in the number of electron dense granules and severe damage to various intracellular organelles including the nucleus.
Juxtaligamental cell cytoplasm contains numerous electron dense granules that are believed to release substances that affect the interaction between the extracellular matrix molecules and cause rapid changes in the mechanical properties of the connective tissue in response to stimuli from the nervous system (Wilkie and Emson, 1987; Wilkie.
Aplysia juliana had large pitted electron dense granules in cells adjacent to rhodoplast digestive cells (Figure 1(b)).
Plasma membrane had undergone shrinkage and developed finger- like outgrowths Electron dense granules could be seen in the space formed between membranes which was a sign of toxicity.
There were also cells transitional between spindle cells and epithelioid cells, with relatively fewer electron dense granules, swollen mitochondria, and occasional stacks of rough endoplasmic reticulum.
sepioidea secretory cells showed differences in organelle abundance between the sexual maturity stages: at the juvenile and immature stages there are numerous mitochondriae, endoplasmic reticulum cisterns are thin and dispersed in the cytoplasm, the Golgi apparatus has a curved profile and actively secretes granules of different densities, whilst in the IV maturation stage (females) and reproductive individuals (males) secretory cells are almost depleted of mitochondriae, endoplasmic reticulum cisterns are dilated and well developed in a concentric fashion, and the Golgi complex actively secretes electron dense granules which are dispersed in the cytoplasm.
They contained abundant electron dense granules within highly elongated cytoplasmic processes.
The mucosal glandular cells were characterized by electron dense granules, a prominent nucleus, mitochondria, and secretory canaliculi forming the tubular vesicle system.
aegypti, Anopheles sp., these substances are synthesized, stored, and released during blood feeding and digestion (Freyvogel & Staubli; Gander, 1968; Okuda et al.); and were observed small electron dense granules in the cytoplasm, which suggests the presence of glycogen.
Both types presented cytoplasmatic characteristics alike, that is, presence of vacuoles of irregular format showing small electron dense granules located on their internal face.

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