electrolyte

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Related to electrolyte disturbances: Electrolyte disorders

electrolyte

 [e-lek´tro-līt]
a chemical substance that, when dissolved in water or melted, dissociates into electrically charged particles (ions) and thus is capable of conducting an electric current. The principal positively charged ions in the body fluids (cations) are sodium (Na+), potassium (K+), calcium (Ca2+), and magnesium (Mg2+). The most important negatively charged ions (anions) are chloride (Cl), bicarbonate (HCO3), and phosphate (PO43−). These electrolytes are involved in metabolic activities and are essential to the normal function of all cells. Concentration gradients of sodium and potassium across the cell membrane produce the membrane potential and provide the means by which electrochemical impulses are transmitted in nerve and muscle fibers.ƒ

The concentration of the various electrolytes in body fluids is maintained within a narrow range. However, the optimal concentrations differ in the extracellular fluid and intracellular fluid. For example, the concentration of sodium in extracellular fluid (serum) is about 15 times higher than in the intracellular fluid. Conversely, the concentration of potassium is about 30 times higher within the cell than in the serum or extracellular fluid.
electrolyte imbalance. This exists when the serum concentration of an electrolyte is either too high or too low. (See accompanying table.) The terms for excessive and deficient blood levels of electrolytes are derived from the Greek prefixes hyper- (over) and hypo- (under), the English or Latin name of the electrolyte, and the Latin suffix -emia. For example, an excess of sodium (Latin, natrium) cations in the serum is called hypernatremia, and a deficit of these ions is called hyponatremia

Stability of the electrolyte balance depends on adequate intake of water and the electrolytes, and on homeostatic mechanisms within the body that regulate the absorption, distribution, and excretion of water and its dissolved particles. Many conditions can interfere with these processes and result in an imbalance. For example, renal disease, in which the kidney nephron is unable to function normally, causes a retention of water, sodium, chloride, bicarbonate, and calcium as the glomerular filtration rate falls. Even when the kidney structures are intact, electrolyte imbalances can result from an inadequate supply of blood to the nephrons or from imbalances of regulatory hormones such as aldosterone and antidiuretic hormone.

The effects of an electrolyte imbalance are not isolated to a particular organ or system. In general, however, imbalances in calcium concentrations affect the bones, kidney, and gastrointestinal tract. Calcium also influences the permeability of cell membranes and thereby regulates neuromuscular activity. Sodium affects the osmolality of blood and therefore influences blood volume and pressure and the retention or loss of interstitial fluid. Potassium affects muscular activities, notably those of the heart, intestines, and respiratory tract, and also affects neural stimulation of the skeletal muscles.

Assessment and nursing interventions related to electrolyte imbalance are shown in the accompanying table.
Electrolyte composition of body fluid.

e·lec·tro·lyte

(ē-lek'trō-līt),
1. Any compound that, in solution or in molten form, conducts electricity and is decomposed (electrolyzed) by it.
2. An ionizable substance in solution.
[electro- + G. lytos, soluble]

electrolyte

/elec·tro·lyte/ (e-lek´tro-līt) a substance that dissociates into ions when fused or in solution, thus becoming capable of conducting electricity.
amphoteric electrolyte  ampholyte; a compound containing at least one group that can act as a base and at least one that can act as an acid.

electrolyte

(ĭ-lĕk′trə-līt′)
n.
1. A chemical compound that ionizes when dissolved or molten to produce an electrically conductive medium.
2. Physiology Any of various ions, such as sodium, potassium, or chloride, required by cells to regulate the electric charge and flow of water molecules across the cell membrane.

electrolyte

[ilek′trōlīt]
Etymology: Gk, elektron + lytos, soluble
an element or compound that, when melted or dissolved in water or another solvent, dissociates into ions and is able to conduct an electric current. Electrolytes differ in their concentrations in blood plasma, interstitial fluid, and cell fluid and affect the movement of substances between those compartments. Proper quantities of principal electrolytes and balance among them are critical to normal metabolism and function. For example, calcium (Ca++) is necessary for relaxation of skeletal muscle and contraction of cardiac muscle; potassium (K+) is required for contraction of skeletal muscle and relaxation of cardiac muscle. Sodium (Na+) is essential in maintaining fluid balance. Certain diseases, conditions, and medications may lead to a deficiency of one or more electrolytes and to an imbalance among them; for example, certain diuretics and a low-sodium diet prescribed in hypertension may cause hypokalemic shock as a result of a loss of potassium. Diarrhea may cause a loss of many electrolytes, leading to hypovolemia and shock, especially in infants. Careful and regular monitoring of electrolytes and IV replacement of fluid and electrolytes are aspects of acute care in many illnesses. electrolytic, adj.

e·lec·tro·lyte

(ĕ-lek'trō-līt)
Any compound that, in solution, conducts electricity and is decomposed (electrolyzed) by it; an ionizable substance in solution.

electrolyte

Any substance which, when dissolved in water, separates into pairs of particles (ions) of opposite charge. For example, sodium chloride (common salt) when dissolved in water forms positive ions of sodium and negative ions of chloride. The electrolytes include salts, acids, alkalis and metal oxides.

Electrolyte

An ion, or weakly charged element, that conducts reactions and signals in the body. Examples of electrolytes are sodium and potassium ions.

electrolyte

a compound that ionizes in solution, conducts and is decomposed by electrical current

e·lec·tro·lyte

(ĕ-lek'trō-līt)
Any compound that, in solution, conducts electricity and is decomposed (electrolyzed) by it.

electrolyte (ēlek´trōlīt),

n a solution that conducts electricity by means of its ions.
electrolyte affinity,
n the attraction of the electrolytes in the body to the different fluid compartments of the intracellular and extracellular environments. Sodium is the predominant cation in the extracellular fluid; potassium is the predominant cation within the cells; chlorine and bicarbonate are the predominant anions in the plasma and interstitial fluids; and phosphates and proteins are the main anions in the cells.
electrolyte balance, fluid and,

electrolyte

a chemical substance which, when dissolved in water or melted, dissociates into electrically charged particles (ions), and thus is capable of conducting an electric current. The principal positively charged ions in the body fluids (cations) are sodium (Na+), potassium (K+), calcium (Ca2+), and magnesium (Mg2+). The most important negatively charged ions (anions) are chloride (Cl), bicarbonate (HCO3−), and phosphate (PO43−). These electrolytes are involved in metabolic activities and are essential to the normal function of all cells. Concentration gradients of sodium and potassium across the cell membrane produce the membrane potential and provide the means by which electrochemical impulses are transmitted in nerve and muscle fibers.
The concentration of the various electrolytes in body fluids is maintained within a narrow range. However, the optimal concentrations differ in the extracellular fluid and intracellular fluid. An electrolyte imbalance exists when the serum concentration of an electrolyte is either too high or too low.
Stability of the electrolyte balance depends on adequate intake of water and the electrolytes, and on homeostatic mechanisms within the body that regulate the absorption, distribution and excretion of water and its dissolved particles.
The effects of an electrolyte imbalance are not isolated to a particular organ or system. In general, however, imbalances in calcium concentrations affect the bones, kidney and gastrointestinal tract. Calcium also influences the permeability of cell membranes and thereby regulates neuromuscular activity. sodium affects the osmolality of blood and therefore influences blood volume and pressure and the retention or loss of interstitial fluid. potassium affects muscular activities, notably those of the heart, intestines and respiratory tract, and also affects neural stimulation of the skeletal muscles.

electrolyte clearance ratio
see fractional excretion tests.
electrolyte disturbances
include hyper- and hypo-potassemia, natremia, phosphatemia, calcemia, chloremia.
electrolyte fluid balance
balance between fluid and electrolytes.
electrolyte homeostasis
maintenance of the osmotic pressure of the blood and tissue fluids by the maintenance of a proper balance between the normal electrolytes in the fluid, and at the same time maintaining adequate concentrations of calcium and magnesium and the proper acid-base balance.
electrolyte solution therapy
see fluid therapy.
References in periodicals archive ?
Hypophosphatemia (abnormally low concentration of phosphate in the blood) is a common electrolyte disturbance in patients treated with CRRT.
This risk may be increased if Strattera is used concomitantly with other drugs that produce QT prolongation, drugs that can cause electrolyte disturbances, and those that inhibit cytochrome P450 2D6.
Certain individuals appear to be more susceptible than others: females; the elderly; individuals with electrolyte disturbances, congestive heart failure and other cardiac abnormalities.
Patients with cardiac, renal, and hepatic diseases as well as water and electrolyte disturbances were retrospectively excluded from the study according to their diagnoses.
Use with caution in patients with impaired renal function, patients with a history of acute phosphate nephropathy, patients with a history of seizures or at higher risk of seizure, patients with higher risk of cardiac arrhythmias, known or suspected electrolyte disturbances (such as dehydration), or people taking drugs that affect electrolyte levels.
These electrolyte disturbances occur when the sodium ion concentration in the plasma is lower than normal and are often associated with a variety of critical care conditions including congestive heart failure, liver failure, kidney failure and pneumonia.
3) Seizures due to significant electrolyte disturbances have been reported.
The pillars of DKA treatment include efforts to correct life-threatening dehydration, hyperglycemia, ketonemia and acidemia, and electrolyte disturbances.
Use with caution in patients with impaired renal function, pre-existing electrolyte disturbances, or people taking drugs that affect electrolyte levels.
Further, there were no orthostatic or electrolyte disturbances, and serial measures of serum creatinine and calculation of glomerular filtration rate (GFR) showed that kidney function in the study cohort remained stable through 12 months.
Hospitalization should only be suggested if the child has severe malnutrition, dehydration, electrolyte disturbances, ECG abnormalities, physiologic instability, arrested growth and development, acute food refusal, uncontrollable binging and purging, acute medical complications of malnutrition, acute psychiatric emergencies, and comorbid diagnosis that interferes with the treatment of the eating disorder.

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