electrochemical gradient


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Related to electrochemical gradient: electrochemical proton gradient

gradient

 [gra´de-ent]
rate of increase or decrease of a variable value, or its representative curve.
edge gradient in radiology, the penumbra or partial shadow on a radiograph caused by the three-dimensional shape of an object.
electrochemical gradient the difference in ion concentration and electrical potential from one point to another, so that ions tend to move passively along it.

e·lec·tro·chem·i·cal gra·di·ent

a measure of the tendency of an ion to move passively from one point to another, taking into consideration the differences in its concentration and in the electrical potentials between the two points; commonly expressed as the additional voltage needed to achieve equilibrium.

electrochemical gradient

a trans MEMBRANE gradient formed as a result of the movement of an ION or other SOLUTE across the membrane. This comprises a gradient of electrical charge and a concentration gradient, which depends on the distribution of the ion across the membrane. Such a gradient can be generated by the operation of an ELECTRON TRANSPORT SYSTEM, in the form of a proton motive force (pmf).
References in periodicals archive ?
Calcium extrusion from the cell across the basolateral membrane occurs against an electrochemical gradient. This transport involves both an ATP-driven calcium transport pump and [Ca.sup.++]-[Na.sup.+] exchange.
Serotonin (5-HT) transport via SERT functions to terminate synaptic serotonergic transmission and is energetically coupled to the inwardly-directed electrochemical gradients of [Na.sup.+] and [Cl.sup.-].
Ion channels are membrane proteins that permit or do not permit ions to pass through cellular membranes according to ion concentration and electrochemical gradients. They are attractive targets for drugs because they provide many opportunities for multiple modes of interaction that can in principal generate a common pharmacological and therapeutic endpoint.

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