(6) Conversely, invasive melanomas tend to push down the elastotic
 In its early phases, SAL shows collapsed parenchyma, focal elastotic
changes, and brisk bile ductular proliferation.
On histology, the stromal collagen has fragmentation and basophilic degeneration known as elastotic
degeneration as the degenerated collagen stains positively when using histochemical stains for elastic fibre like the Verhoeff-Van Gieson stain.
changes were detected in the LC of eyes with PXG.
When a patient presents with major lines in the perioral area, an "orange peel" texture, and/or elastotic
changes, laser resurfacing can be an appropriate option.
Increased elastic tissue and solar elastotic
Lungarella et al., "UVA light stimulates the production of cathepsin G and elastase-like enzymes by dermal fibroblasts: a possible contribution to the remodeling of elastotic
areas in sun-damaged skin," Biological Chemistry, vol.
Acquired disorders of elastic tissue: Part I: Increased elastic tissue and solar elastotic
This change may be representing aging or elastotic
degeneration due to chronic sun exposure.
The differential diagnosis includes benign or malignant cutaneous tumors, such as basal cell carcinoma, keratoacanthoma, squamous cell carcinoma actinic keratosis, atypical fibroxanthoma , cystic chondromalacia, elastotic
nodules of the ears, Merkel cell carcinoma, perforating dermatoses, gouty tophi, verruca vulgaris, molluscum contagiosum, cutaneous horn and pseudocyst of the auricle.
They result from elastotic
degeneration of the collagen fibres or could be a product of abnormal elastogenesis or even a combination of both processes.
Exposure of skin to ultraviolet (UV) radiation can lead to deposition of excessive elastotic
material, reduction in collagen, and increased expression of matrix metalloproteinases (MMPs).