elastolysis

[e″las-tol´ĭ-sis]

a defect in the elastic tissue, resulting in atrophy and laxity of the skin.

e·las·tol·y·sis

(ē-las-tol'i-sis),

Dissolution of elastic fibers.

[elasto- + G. lysis, loosening, fr. luō, to loosen]

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References in periodicals archive ?

At the same time, recirculating flow into the aneurysm sac is amongst the most important factors that lead to further expansion of aneurysm and its rupture [27, 28], inducing a profound shift of the artery wall towards elastolysis, inflammation, and oxidative stress.

Treatment of Aortic and Iliac Artery Aneurysms with Multilayer Flow Modulator: Single Centre Experiences

ECM degradation enzymes, such as MMPs and cathepsins, are produced by macrophages and result in elastolysis and alveolar tissue damage [179-182].

Dysregulated Functions of Lung Macrophage Populations in COPD

The differential diagnoses mainly include anetoderma, mid-dermal elastolysis, focal dermal hypoplasia, lupus panniculitis, and localized scleroderma.

Local Panatrophy Associated with Pain: A Rare Variant of Local Panatrophy or a New Entity?

Middermal elastolysis (MDE) is a rare disease of dermal connective tissue, described for the first time by Shelley and Wood in 1977, as "wrinkles due to idiopathic loss of elastic tissue of the middermis" [1].

Middermal Elastolysis: Dermal Fibroblasts Cooperate with Inflammatory Cells to the Elastolytic Disorder

These changes include mast cell degranulation and the presence of activated macrophages in association with mid-dermal elastolysis. (23) When the lesions become become clinically visible, collagen bundles start showing structural alterations, fibroblasts become prominent, and mast cells are absent.

Striae distensae: what's new at the horizon?

Type 3 includes patients of MKS with evidence of extrapulmonary elastolysis. Persons with Type 4 MKS have no clear predisposing factors.

Tracheobronchomegaly as a Cause of Bronchiectasis in an Adult

DISCUSSION: (1, 2, 3) Cutis laxa (Latin for loose or lax skin) also known as Generalized Elastolysis / Dermatomegaly / Dermatolysis / Dermatochalasia / Generalized elastorrhexis / Pachydermatocele is an Orphan disease (a very rare disease) related to a heterogeneous connective tissue disorder in which the skin becomes inelastic and hangs loosely in folds.

Congenital cutis laxa with pneumonia: a rare case in pediatric practice

(13) A characteristic finding is the presence of extensive collagenolysis and elastolysis, resulting in "floating fat" separated from the surrounding reticular dermis and the pannicular septa.

Neutrophilic Panniculitis: Algorithmic Approach to a Heterogeneous Group of Disorders

For example, aging causes the loss of elastin natural properties, and thus it becomes susceptible to deposition of calcium and elastolysis. Enhanced decomposition of insoluble elastin in the vascular wall leads to the appearance of peptides in the blood stream, whereas anti-elastin antibodies are created in response to them [17].

The relationship between atherosclerosis and pulmonary emphysema/Povezanost ateroskleroze i emfizema pluca

Then activation of matrix metalloproteinase 2 causes elastolysis of elastin and fibrillar collagen in arterial media.

Serum homocysteine as a risk factor in diabetics with colour vision deficiency and for developing retinopathy

On the other hand, genetic factors such as Marfan's syndrome, vascular Ehlers-Danlos syndrome, bicuspid aortic valve, and familial aortic dissection contribute to a compromised intima and aortic dissection through differentiation of the vascular smooth muscle cells and enhanced elastolysis of the aortic wall components [3].

A perspective review on numerical simulations of hemodynamics in aortic dissection

Collagen bundles appear to unravel, and the individual elastic fibers show signs of elastolysis. The net effect of these fibrous rearrangements and alterations is a dermis that is less stretchable, less resilient, more lax, and prone to wrinkling.