(8) Tunica media consists almost entirely of concentric circularly arranged, fenestrated
elastic lamella between which are found smooth muscle cells and surrounding which are collagen fibres, the whole being imbued with a matrix of ground substance.
Tunica media was separated from intima by internal elastic lamella and it was separated from tunica adventitia by external elastic lamella.
Tocotrienol treatment of diabetic mice reduced vascular smooth muscle cells proliferation and disruptions of elastic lamella in media which was also supported by Budin et al.
