efflux


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efflux

Medtalk That which flows outward

efflux

(ĕf′lŭks) [″ + ″]
Outward flow, i.e., the movement of chemicals or other fluids from within a structure, such as a cell, to the outside.
References in periodicals archive ?
The Ethidium Bromide-agar Cartwheel (EtBrCW) method proved to be a valuable tool for the rapid and simple screening of efflux pump activity, (17) for five clinical isolates of selected MDR S.
Interplay of efflux system, ampC, and oprD expression in carbapenemo resistance of Pseudomonas aeruginosa clinical isolates.
The apparent permeability of digoxin is markedly reduced in the presence of P-gp inhibitors indicating that digoxin is subject to P-gp-mediated efflux in Caco-2 cells.
aeruginosa is inherently resistant to antimicrobial agents because of restricted access of extracellular antimicrobial agents to intracellular targets, active efflux of antimicrobial agents out of the cell and production of enzymes that degrade antimicrobial agents.
Twenty-one of the 98 isolates had efflux for Cip; 3 of them also had efflux for levofloxacin (Tables 2, 3), and none had efflux for moxifloxacin.
eigenmanni would reduce gill ventilation and oxygen uptake, which would lead to a decrease of gill ion efflux and, consequently, reducing ion loss, as observed.
LABORATORY ASSESSMENT OF CHOLESTEROL EFFLUX AND REVERSE CHOLESTEROL TRANSPORT
The major point of our article (Luckenbach and Epel 2005) was that the musks inhibit efflux (drug) transporters, which act as first lines of defense to pump potentially toxic substances out of cells.
Musks are classified as nitromusks and polycyclic musks Two nitromusks, at concentrations of less than 1 micromole per liter ([micro]M/l), suppressed by half the normal activity of the cells' efflux pumps, Epel and Luckenbach report in the January Environmental Health Perspectives.
Current ambient levels of synthetic musks in North American waters are far below the threshold known to shut down a cell's efflux transport system.
Autism meets the criteria of being an efflux disease, said H.