effector cell


Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia, Wikipedia.

ef·fec·tor cell

a terminally differentiated leukocyte that performs one or more specific functions.
See also: effector.

effector cell

A cell that carries out the final response or function of a particular process. The main effector cells of the immune system, for example, are activated lymphocytes and phagocytes—the cells involved in destroying pathogens and removing them from the body.
See: leukocyte
See also: cell
References in periodicals archive ?
Regulatory Role of [CD4.sup.+] T Effector Cells in Progression of Myocarditis to iDCM
In this assay (Figure 1), Jurkat cell lines, stably expressing NFAT-luciferase reporter and human FcyRIIIa (both variants have been transduced; currently, only the V158 variant is commercially available), are used to replace primary NK cells isolated from PBMCs as effector cells, while WIL2-S cells expressing the CD-20 antigen specific to the test products are used as target cells.
If sIgE/T-IgE ratio increases, sIgE density increases closer to the resides closer to each other on the surface of effector cells. After allergen re-exposure, the probability of inflammatory factors released from activated effector cells will increase.
NK cells are vital immune effector cells and play important roles in immune surveillance.
A master cell bank (MCB) and a working cell bank (WCB) were prepared for the clonal effector cell lines and each of the clonal target cell lines.
The role and difference of specific effector cell population have gained more attention in recent years as another important aspect for effective adoptive immunotherapy.
Discovered through an unbiased functional screening of multiple immunomodulatory target combinations, the differentiated profile of MCLA-145 derives from its potential to attract T cells into solid tumors, potently activate immune effector cells in the context of the tumor microenvironment and simultaneously block inhibitory signals in the same immune cell population.
Vopratelimab treatment resulted in the emergence of ICOS hi CD4 T effector cells in the peripheral blood and emergence of these cells was associated with response and improvements in progression free survival and overall survival, as presented at the 2019 American Association for Cancer Research Annual Meeting," said CMO Beth Trehu.
SX-682 exhibits mono-agent anti-tumour activity, blocks metastasis, depletes immunosuppressive myeloid cells, activates tumour killing by effector cells, reverses chemo-resistance as well as potently synergizes with anti-CTLA-4 and anti-PD1.
Interferons signal other cells to take action by turning on the expression of genes that inhibit viral replication, activate immune effector cells, and increase host defenses.
Both neural and hormonal routes of communication allow the brain to influence intestinal activities, including activity of functional effector cells (i.e., immune cells, epithelial cells, enteric neurons, smooth muscle cells, interstitial cells, etc.).