Sepsis attenuates the intensity of the neuromuscular blocking effect of d-tubocurarine and the antagonistic actions of neostigmine and edrophonium
accompanying depression of muscle contractility of the diaphragm.
This test is carried out by intravenous (IV) injection of edrophonium
(Tensilon) and then by following the development of muscle weakness in the next 30-90 seconds.
ANTICHOLINESTERASE DRUGS: Renal excretion accounts for approximately 50% of the clearance of neostigmine and approximately 75% of elimination of edrophonium
chloride test was interpreted as positive for myasthenia gravis, and intravenous immune globulin treatment was initiated.
A test dose of edrophonium
to assess whether anticholinesterase therapy may be of benefit is generally recommended.
Test results from a complete blood count, biochemistry profile, whole-body radiographs, needle electromyography of the leg muscles, and an edrophonium
challenge test were within reference limits.
Sugammadex reversal of rocuronium-induced neuromuscular blockade: a comparison with neostigmine-glycopyrrolate and edrophonium
6 nmol/I) and a clear improvement in eye muscle weakness a few seconds after the administration of edrophonium
Diagnostic Tests: CBC, serum chemistry, radiographs, radiographic contrast studies, muscle biopsy, and edrophonium
With Tensilon[TM] testing, edrophonium
, whose trade name is Tensilon[TM], is injected into a vein and the LEMG is repeated.
Electromyography testing, edrophonium
test, and antibody tests are used in conjunction with the clinical and neurological history and exam to support a diagnosis of MG.
Separation and detection of a mixture of 4 cationic inhibitors--tacrine, edrophonium
, and tetramethyl- and tetraethyl-ammonium chloride--was accomplished within 70 s with a multiplexed screening device combining flow injection analysis and microchip CE separation.