edrophonium


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edrophonium

 [ed″ro-fo´ne-um]
a cholinergic used in the form of the chloride salt as a curare antagonist and diagnostic agent in myasthenia gravis.

edrophonium

/ed·ro·pho·ni·um/ (ed″ro-fo´ne-um) a cholinergic used in the form of the chloride salt as a curare antagonist and as a diagnostic agent in myasthenia gravis.

edrophonium

A drug that inactivates the enzyme CHOLINESTERASE that breaks down ACETYLCHOLINE. It is used as a test for MYASTHENIA GRAVIS, a disease in which the action of acetyl choline is impaired. The brand name is Tensilon.

edrophonium

a cholinergic used in the form of the chloride salt as a curare antagonist; used in the edrophonium challenge test to diagnose myasthenia gravis. See also tensilon.
References in periodicals archive ?
Sepsis attenuates the intensity of the neuromuscular blocking effect of d-tubocurarine and the antagonistic actions of neostigmine and edrophonium accompanying depression of muscle contractility of the diaphragm.
This test is carried out by intravenous (IV) injection of edrophonium (Tensilon) and then by following the development of muscle weakness in the next 30-90 seconds.
ANTICHOLINESTERASE DRUGS: Renal excretion accounts for approximately 50% of the clearance of neostigmine and approximately 75% of elimination of edrophonium and pyridostigmine.
An edrophonium chloride test was interpreted as positive for myasthenia gravis, and intravenous immune globulin treatment was initiated.
A test dose of edrophonium to assess whether anticholinesterase therapy may be of benefit is generally recommended.
Test results from a complete blood count, biochemistry profile, whole-body radiographs, needle electromyography of the leg muscles, and an edrophonium challenge test were within reference limits.
Sugammadex reversal of rocuronium-induced neuromuscular blockade: a comparison with neostigmine-glycopyrrolate and edrophonium atropine.
Diagnostic Tests: CBC, serum chemistry, radiographs, radiographic contrast studies, muscle biopsy, and edrophonium challenge test.
With Tensilon[TM] testing, edrophonium, whose trade name is Tensilon[TM], is injected into a vein and the LEMG is repeated.
Electromyography testing, edrophonium test, and antibody tests are used in conjunction with the clinical and neurological history and exam to support a diagnosis of MG.
Separation and detection of a mixture of 4 cationic inhibitors--tacrine, edrophonium, and tetramethyl- and tetraethyl-ammonium chloride--was accomplished within 70 s with a multiplexed screening device combining flow injection analysis and microchip CE separation.