ectromelia


Also found in: Encyclopedia.

ectromelia

 [ek″tro-me´le-ah]
gross hypoplasia or aplasia of one or more long bones of one or more limbs. adj., adj ectromel´ic.

ec·tro·me·li·a

(ek'trō-mē'lē-ă),
1. Congenital hypoplasia or aplasia of one or more limbs.
2. A disease of mice caused by the ectromelia virus, a member of the family Poxviridae; characterized by gangrenous loss of feet and by necrotic areas in the internal organs; in laboratory mouse colonies, it usually results in high mortality rates.
[ectro- + G. melos, limb]

ec·tro·me·li·a

(ek'trō-mē'lē-ă)
1. Congenital hypoplasia or aplasia of one or more limbs.
2. A disease of mice caused by the ectromelia virus; characterized by gangrenous loss of feet and necrotic areas in the internal organs; in laboratory mouse colonies, it usually results in high mortality rates.
[ectro- + G. melos, limb]
References in periodicals archive ?
The contribution of the secreted type I IFN binding protein to virus virulence and immune evasion becomes evident in mouse models of VACV and ectromelia virus infection, where mutant viruses show an attenuated phenotype that is dramatic in the mousepox model [13, 23].
Christensen, et al., "Expression of Mouse Interleukin-4 by a Recombinant Ectromelia Virus Suppresses Cytolytic Lymphocyte Responses and Overcomes Genetic Resistance to Mousepox," Journal of Virology 75, no.
A smallpox diagnostic panel compiled by Inger Damon s laboratory at the CDC included 12 different variola virus isolates (VAR), 13 different strains and isolates of camelpox, cowpox (CPV), ectromelia, herpes, monkeypox, Staphylococcus aureus, vaccinia (VV), and varicella-zoster viruses (VZV).
En cambio Rainwater [43] reporta dos casos de ectromelia (ausencia de un miembro) en Crocodylus moreletti.
Dr Ron Jackson, Dr Deborah Maguire, Dr Lyn Hinds and Professor Ian Ramshaw infected laboratory mice with an ectromelia (mouse pox) virus equipped with a gene coding for zone pellucida proteins.
Ectromelia virus (ECTV) is the causative agent of mousepox, a severe exanthematous disease of mice in laboratory colonies and has been reported worldwide in several outbreaks and causes high economic losses in biomedical research (6).
KEY WORDS: congenital abnormalities, ectromelia, farmworkers, fungicides, Goldenhar Syndrome, insecticides, micrognathism, pesticides, prevention and control, toxicity.
We evaluated the specificity of the PPV real-time PCR assay by use of DNA from several viruses, including orthopoxviruses (vaccinia, cowpox, monkeypox, ectromelia, and camelpox virus), molluscum contagiosum virus, yaba-like disease virus, human herpesviruses types 1 to 8, and adenoviruses.
Some orthopoxviruses have limited host ranges; for example ectromelia virus (ECTV) has only been described infecting captive colonies of laboratory mice (2,3).
A panel of 15 lyophilized plasma samples to which gamma-irradiated, heat-inactivated orthopox viruses (MPV, CPV, VAC, CML, and ectromelia virus) had been added was provided by the European Network for the Diagnosis of Imported Viral Diseases (ENIVD; Berlin, Germany).
Practical PCR testing using DNA from cowpox, monkeypox, ectromelia, parapox-ORF, myxoma, avipox, and molluscipox viruses showed no cross-reactivity.