ectoenzyme


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ectoenzyme

 [ek″to-en´zīm]
an extracellular enzyme.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ec·to·en·zyme

(ek'tō-en'zīm),
1. An enzyme that is excreted externally and that acts outside the organism.
2. An enzyme that is attached to the external surface of the plasma membrane of a cell.
Farlex Partner Medical Dictionary © Farlex 2012

ec·to·en·zyme

(ek'tō-en'zīm)
An enzyme that is excreted externally and that acts outside the organism.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
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References in periodicals archive ?
These ectoenzymes are anchored to the plasma membrane via hydrophobic domains with the active site facing the extracellular medium [5, 38, 48].
Myeloid-derived suppressor cells (MDSC) and mesenchymal stem cells (MSC) are populations with regulatory functions, characterized by the presence of adenosinergic ectoenzymes. A recent report indicates that [CD11b.sup.+][CD33.sup.+] MDSC in peripheral blood and tumor tissues from nonsmall cell lung cancer (NSCLC) patients express surface ectonucleotidases CD39 and CD73.
ALP, OCN, and Col-1 are markers capable of detecting early osteogenic cell differentiation [28]; by contrast, ALP acts as an ectoenzyme in the degradation of inorganic pyrophosphate for releasing phosphate for mineralization [18].
A key indicator of osteoblast maturation is the membrane-bound ectoenzyme alkaline phosphatase (ALP).
BSK_SAg_CD38_up Novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes.
A gene expression study carried out by Corton et al (66) with omental adipose tissue from PCOS women showed overexpression of ectoenzyme nucleotide pyrophosphate phosphodiesterase 1 (ENPPI), which is a negative regulator of INSR tyrosine kinase activity and the regulatory p85[alpha] subunit of PI3K which resulted in decreased PI3K activity.
CD38 is an ectoenzyme important to the metabolism of activated T lymphocytes, an adhesion receptor involved in the migration of lymphocytes into peripheral tissues and a signalling molecule responsible for T cell co-stimulation and B cell maturation [33,34].
The test detects upregulation of CD203c, an ectoenzyme expressed only on basophils, mast cells, and CD34-positive progenitor cells in peripheral blood as a marker of cell activation, said Dr.
Lymphocyte ectoenzyme activity compared in healthy persons and patients seropositive to or at high risk of HIV infection.
Acetylcholinesterase (AChE) is a membrane-bound enzyme with its active side exposed at the external leaflet of the bilayer (ectoenzyme).
CD203c (ectonucleotide pyrophosphatase/ phosphodiesterase) is an ectoenzyme which is only expressed on basophils, mast cells, and their CD34 [96] progenitor cells in the peripheral blood [97].