econazole


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econazole

 [ĕ-kon´ah-zōl]
an imidazole derivative used as the nitrate salt as a broad-spectrum antifungal agent, applied topically in the treatment of cutaneous candidiasis and various forms of tinea.

econazole

/econ·a·zole/ (ĕ-kon´ah-zōl) an imidazole derivative used as the nitrate salt as a broad-spectrum antifungal agent.

econazole

(ĭ-kŏn′ə-zōl′)
n.
A broad-spectrum antifungal agent used in the treatment of athlete's foot and related fungal infections.

econazole

[ikon′əzōl]
a topical antifungal agent.
indications It is prescribed in the treatment of tinea pedis, tinea cruris, tinea corporis, tinea versicolor, and candidiasis.
contraindication Known sensitivity to this drug prohibits its use.
adverse effects Among the most serious adverse effects are local irritation and hypersensitivity of the skin.

econazole

A broad-spectrum antifungal drug used in local (topical) application. Brand names are Ecostatin, Pevaryl, Pevaryl TC and Gyno-Pevaryl.

antifungal agent 

Any substance which destroys or prevents the growth of fungi. It is one of the antibiotic groups. There are several classes of antifungal drugs: Polyenes, which cause an increase in fungal cell wall permeability leading to its death. Examples: amphotericin B, natamycin, nystatin. Azoles, which act either by inhibiting the synthesis of ergosterol, a component of fungal cell wall or by causing direct wall damage. Examples: clotrimazole, econazole, fluconazole, itraconazole, ketoconazole, miconazole. Pyrimidines, which interfere with the normal function of fungal cells. Example: flucytosine. Syn antimycotic agent.

econazole

an imidazole antifungal agent related to miconazole; used topically as the nitrate in the treatment of fungal infections of the skin.
References in periodicals archive ?
For candida species, all were susceptible to amphotericin B, nystatin, fluconazole, flucytosine, ketoconazole and econazole, while 3(60%) were resistant to miconazole.
Pharmaceutical company IGI Laboratories Inc (NYSE MKT:IG) reported on Friday the receipt of formal approval of its supplemental filing for the site transfer of econazole nitrate cream 1% to its manufacturing facility in Buena, NJ.
In a 4-week study involving 104 patients, naftifine 1% cream (Naftin) was compared with econazole 1% cream (Spectazole) (both applied twice daily).
In Switzerland, three triazoles (terconazole, itraconazole, fluconazole) and eight imidazoles (clotrimazole, miconazole, econazole, ketoconazole, tioconazole, isoconazole, oxiconazole, and fenticonazole) are in use (Documed AG 2002).
M2 EQUITYBITES-February 5, 2013-IGI Laboratories Inc announces acquisition of Econazole Nitrate Cream for undisclosed sum(C)2013 M2 COMMUNICATIONS http://www.
In vitro activities of ketoconazole, econazole, miconazole, and Melaleuca alternifolia (tea tree) oil against Malassezia species.
A Clinical Evidence review (16) identified 1 trial comparing intravaginal miconazole, clotrimazole, econazole, and nystatin; symptomatic relapse was lower with intravaginal imidazoles than with nystatin.
purpurea was studied on 203 women with recurrent vulvovaginal candidiasis who were being treated with a topical econazole nitrate cream.
Topical members of this class are clotrimazole, miconazole, econazole, ketoconazole, oxiconazole, and sulconazole.
The Cochrane Database of Systemic Reviews (1,2) reported 72 placebo-controlled trials of topical agents that yielded the following cure rates: undecenoic acid, 72%; allylamines (terbinafine, naftifine, butenafine), 70%; tolnafrate, 64%; azoles (miconazole, clotrimazole, ketoconazole, econazole, oxiconazole), 47%.