econazole


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econazole

 [ĕ-kon´ah-zōl]
an imidazole derivative used as the nitrate salt as a broad-spectrum antifungal agent, applied topically in the treatment of cutaneous candidiasis and various forms of tinea.

econazole

(ĭ-kŏn′ə-zōl′)
n.
A broad-spectrum antifungal agent used in the treatment of athlete's foot and related fungal infections.

econazole

A broad-spectrum antifungal drug used in local (topical) application. Brand names are Ecostatin, Pevaryl, Pevaryl TC and Gyno-Pevaryl.

antifungal agent 

Any substance which destroys or prevents the growth of fungi. It is one of the antibiotic groups. There are several classes of antifungal drugs: Polyenes, which cause an increase in fungal cell wall permeability leading to its death. Examples: amphotericin B, natamycin, nystatin. Azoles, which act either by inhibiting the synthesis of ergosterol, a component of fungal cell wall or by causing direct wall damage. Examples: clotrimazole, econazole, fluconazole, itraconazole, ketoconazole, miconazole. Pyrimidines, which interfere with the normal function of fungal cells. Example: flucytosine. Syn antimycotic agent.
References in periodicals archive ?
The authors wish to thank Gufic Biosciences Ltd., Navsari, Guj arat, India, for kindly providing the gift sample of the drug econazole nitrate.
Econazole and miconazole have also been used intravenously, but absorbed levels are usually too low for treatment of systemic mycoses.
In this test, seven antifungal agents were used, including amphotericin B (4ug/ml), nystatine (200 units/ml), flucytosine (35ug/ml), econazole (16ug/ml), ketoconazole (16ug/ml), miconazole (16ug/ml) and fluconazole (16ug/ml).
Pharmaceutical company IGI Laboratories Inc (NYSE MKT:IG) reported on Friday the receipt of formal approval of its supplemental filing for the site transfer of econazole nitrate cream 1% to its manufacturing facility in Buena, NJ.
EcoNail is the company's patented lacquer which contains the antifungal econazole and MacroChem's enhancer SEPA.
Econazole is unique among azoles in that studies show it has antibacterial properties, he noted.
The fungicidal allylamines (naftifine and terbinafine) and butenafine (allylamine derivative) are a more costly group of topical tinea treatments, yet they are more convenient as they allow for a shorter duration of treatment compared with fungistatic azoles (clotrimazole, econazole, ketoconazole, oxiconazole, miconazole, and sulconazole).
Drug Dosage Cost/Tube * ciclopirox twice a day $31.83 (Loprox) clotrimazole twice a day $14.87 econazole once or $28.70 (Spectazole) twice a day ketoconazole once or $31.78 twice a day naftifine twice a day $31.73 (20 (Naftin) g); $54.40 (40 g) terbinafine twice a day $58.40 (Lamisil) SYSTEMIC AGENTS Drug Dosage Cost/Day ** terbinafine 250 mg/day $8.68 (Lamisil) itraconazole 200-400 $15.56 (200 (Sporanox) mg/day mg) Drug Comment ([dagger]) ciclopirox Pyradone, formulated as cream, gel, lotion, and topical (Loprox) suspension.
In Switzerland, three triazoles (terconazole, itraconazole, fluconazole) and eight imidazoles (clotrimazole, miconazole, econazole, ketoconazole, tioconazole, isoconazole, oxiconazole, and fenticonazole) are in use (Documed AG 2002).
Bassiouny et al (12) studied the effects of antifungal agents and found that clotrimazole and econazole were effective antifungal agents in the treatment of otomycosis.
M2 EQUITYBITES-February 5, 2013-IGI Laboratories Inc announces acquisition of Econazole Nitrate Cream for undisclosed sum(C)2013 M2 COMMUNICATIONS http://www.m2.com
In vitro activities of ketoconazole, econazole, miconazole, and Melaleuca alternifolia (tea tree) oil against Malassezia species.