Eclampsia is a form of hypertensive disorder of pregnancy characterized by occurrence of tonic-clonic convulsions in patient having hypertension and proteinuria, however 20% of
eclamptics are normotensive and non proteinuric.
05) was noted in the total cholesterol, low density lipoprotein-cholesterol, apolipoprotein B100, low density lipoprotein: apolipoprotein B100 ratio and high density lipoprotein: apolipoprotein A1 in
eclamptic patients and normotensive pregnant women.
According to the prevailing, forced dilatation theory, a rapid rise in blood pressure (BP), which exceeds the upper limit of cerebral autoregulation, leads to the blood brain barrier (BBB) dysfunction, cerebral vasodilatation and local hyperperfusion, manifested by vasogenic edema present in 93-100% of
eclamptic women.
In
eclamptic women, however, the median gestational ages for perinatal deaths and survivors were term (37 versus 38 weeks).
Eclamptic patients who had received any anticonvulsant elsewhere before referral to our centre were excluded from the study as were those with added complications like stroke, renal failure and heart failure.
One midwife had to attend three patients with severe
eclamptic fits in the intensive care unit.
Evidence shows that magnesium sulphate more than halves the risk of
eclamptic seizures (44).
The average time from index pregnancy was not significantly different between the formerly
eclamptic and normotensive groups (7 years vs.
Pre-
eclamptic and
eclamptic patients are at risk from an exaggerated hypertensive response to intubation, potentially resulting in cerebrovascular haemorrhage or pulmonary oedema.
It's very important that these women are treated adequately right away when they come in with headaches so we can prevent more
eclamptic seizures," Ms.
Magnesium is the drug of choice to prevent or control
eclamptic seizures, as it does not cause significant depression of the maternal and neonatal central nervous systems; Goldstein & Stem, 1992).
The Scots team are teaching local medical staff the skills to handle difficult births, such as preventing women dying through haemorrhaging or
eclamptic fit, and the resuscitation of newborns.
