echinocandin


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echinocandin

(ē-kī-nō-kan'din),
A class of antifungal compounds targeting the fungal cell wall. Action is by specific and noncompetitive inhibition of the (1,3)-β-d-glucan synthase enzyme complex that forms glucan polymers; a major component of the fungal cell wall in several pathogenic fungi.

echinocandin

(ē-kī″nō-kan′din) [Gr. echinos, hedgehog, sea urchin, + Cand(ida albicans) + -in]
Any of a class of antifungal drugs that block the synthesis of the fungal cell wall.
References in periodicals archive ?
In view of the degenerating condition, amikacin was added to her treatment and liposomal amphotericin B was replaced with Echinocandin (caspofungin acetate) at a dose of 50mg following a loading dose of 70mg, for suspected refractory Aspergillus infection.
Caspofungin recently became the first echinocandin to win approval, for the treatment of aspergillosis, and probably soon will be approved for the treatment of candidemia, said Dr.
Data from this expanded surveillance are used to describe candidemia in these populations and to evaluate the emergence of echinocandin resistance in C.
Disseminated trichosporonosis has been reported in immunocompromised patients under echinocandin therapy.
The company is developing the product, a novel long-acting agent in the echinocandin class of antifungals, for the treatment of systemic Candida infections, including candidemia and related cases of invasive candidiasis.
Contract award: tender for the supply of echinocandin for systemic mycosis 74/2014
An intravenous antifungal of the echinocandin class for treating candidemia and other forms of Candida infection (intraabdominal abscess, peritonitis, and esophageal candidiasis).
ERAXIS (anidulafungin) for Injection belongs to the echinocandin class of antifungal drugs and is used to treat serious fungal infections caused by Candida, a yeast commonly found on the skin, in the digestive tract, or as a contaminant on medical equipment and devices.
However, subsequent analyses identified increases in echinocandin-resistant and multidrug-resistant Candida infections during 2008-2012 (13); evaluation of the emergence of echinocandin resistance in C.
Micafungin (Mycamine), an echinocandin antifungal agent, is indicated for prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation and for treatment of esophageal candidiasis.