Of particular note was the absence of infusion-related histamine reactions, a recognized effect of other drugs in the echinocandin
class, and the lack of a significant infusion-associated rise in plasma histamine levels, even at the highest doses and concentrations of administered drug.
Cancidas currently enjoys the largest share of courses within the echinocandin
class (66 percent), followed by Mycamine (22 percent) and Eraxis (13 percent)," stated Joyce Wedemeyer, product director at AMR.
LY303366, intraconazole and amphotericin B.
This finding has stimulated interest in combinations of voriconazole and terbinafine (26), voriconazole and echinocandin
(36), or polyene and echinocandin
CANCIDAS is a member of the echinocandin
class of antifungals.
Aminocandin is a member of the echinocandin
class of anti-fungal agents, the first new class of such agents to be developed and introduced in more than 40 years.
We are currently conducting a multiple dose Phase I trial with aminocandin to test the safety and pharmacokinetics of this echinocandin
compound for the therapy of serious fungal infections," said Dr.
International surveillance of bloodstream infections due to Candida species in the European SENTRY program: species distribution and antifungal susceptibility including the investigational triazole and echinocandin
Caspofungin recently became the first echinocandin
to win approval, for the treatment of aspergillosis, and probably soon will be approved for the treatment of candidemia, said Dr.
at Columbia University Medical Center demonstrated that rapid PNA FISH results led to an early switch to caspofungin, an echinocandin
, for 81% of patients with C.
, polyene, or both, but only 1 of those 3 patients survived.
analysis - historical and future outlook 231