The chemical structure of azadirachtin is similar to that of ecdysone
, an insect hormone that regulates metamorphosis.
agonists (methoxyfenozide and tebufenozoide) are on second place in term of their effectiveness after CSIs.
This insecticide acts as ecdysone
Developmental regulation of ecdysone
receptor (EcR) and EcR-controlled gene expression during pharate-adult development of honeybees (Apis mellifera).
aerogene, and Serratia marcesensesi with active compounds included a-sitosterol, hydroxy ecdysone
, ecdysterone, and giloinsterol (39,40).
In the assay, 20E and ecdysone
are nearly equally recognized by the polyclonal AS 4919 antibodies used (Porcheron et al.
: Structures and Functions Chapter 23:551-578.
The diacyl hydrazines act as ecdysone
antagonists, promoting acceleration in the ecdysis process (Dhadialla et al.
The expression of Pc-14-3-3 was significantly up-regulated in hepatopancreas after eyestalk ablation or ecdysone
induction, which was confirmed by qRT-PCR and western blot analysis.
In the CC-CA of mosquitoes, the expression of the following receptors has been detected: ETH A and B, ecdysone
A and B, insulin, ultraspiracle A and B, allatotropin, AST-C A and B, and the short neuropeptide F.
To date, only one BTB protein, broad complex (BR-C) protein of the BTB-ZF subfamily, has been identified in the silkworm, where it has been shown to mediate ecdysone
signaling [29, 30].