eccrine spiradenoma

ec·crine spi·rad·e·no·ma

a typically painful benign skin tumor composed of two cell types derived from the secretory part of eccrine sweat glands.
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Other entities to be considered in the differential diagnosis include: inclusion cysts, giant cell tumor, foreign body reaction, eccrine spiradenoma, osteoma cutis, trichilemmal cyst, hydrocystoma, basal cell carcinoma, calcification in lymph node, fat necrosis, pyogenic granuloma, lymphadenopathy, fibroxanthoma, chalazion and keratoacanthoma.
Histochemistry of hidradenoma and eccrine spiradenoma.
On malignant transformation of eccrine spiradenoma [in Polish].
Malignant eccrine spiradenoma (spiradenocarcinoma): a clinicopathologic study of 12 cases.
On the basis of pathologic findings, the differential diagnoses include eccrine adenocarcinoma not otherwise specified (NOS), porocarcinoma, apocrine carcinoma, malignant chondroid syringoma, and eccrine spiradenoma.
10) Similarly, malignant eccrine spiradenoma was excluded on the basis of the absence of benign eccrine spiradenoma cells.
Eccrine spiradenoma is now known as a benign sweat gland tumor that commonly affects young adults.
Other tumors with eccrine differentiation are malignant cylindroma, malignant eccrine poroma, malignant eccrine spiradenoma, malignant nodular hidradenoma and malignant chondroid syringoma.
Here we describe a unique and a rare case of malignant eccrine spiradenoma which mimicked like a basal cell carcinoma, squamous cell carcinoma or a malignant melanoma.
Eccrine spiradenomas are painful dermal nodules composed of lobular arrangement of two types of epithelial cells--one with scant cytoplasm and dark nuclei in the periphery and the other with large pale nuclei in the center of lobules.
Patients may also develop facial trichoepitheliomas, eccrine spiradenomas, and milia, with highly variable expressivity.
3 Painful skin lesions, such as granular cell tumours, eccrine spiradenomas, dermatofibromas, neuromas, neurilemmomas, glomus tumours, angiolipomas and endometriomas, should be considered in the differential diagnosis of cutaneous leiomyomas.