Comparison of two doses and two routes of administration of misoprostol after pre-treatment with mifepristone for early pregnancy termination
. Reprod Health 2008;5:2.
Manual vacuum aspiration, a safe and effective alternative in early pregnancy termination
. Acta Obstet Gynecol Scand 2001; 80: 563-7.
Some case series report maternal and fetal mortality rates of 11-50 percent when pregnancy is complicated by pulmonary hypertension; (10-12) thus, expert consensus guidelines strongly recommend early pregnancy termination
in women with PAH.
Sublingual misoprostol is also widely used for early pregnancy termination
. In a study that compared the repeated doses of sublingual or vaginally administrated of 600 mcg misoprostol every 3 h up [up to three doses] the authors demonstrated the success rate was similar in both groups [about 87.5%].
In many settings where mifepristone is unavailable, misoprostol is commonly used alone for early pregnancy termination
. Misoprostol was originally developed in the mid-1980s for gastrointestinal indications and is licensed for such purposes in about 90 countries worldwide.
(1) WHO currently includes misoprostol in its Model List of Essential Medicines for early pregnancy termination
, medical management of miscarriage and labour induction.
Acceptability and feasibility of early pregnancy termination
Elsewhere the authors stated: "this frequency of adverse outcome in the offspring of alcoholic women is sufficiently high to merit serious consideration of early pregnancy termination
for the chronically alcoholic woman." Kenneth Lyons Jones, et a1, "Incidence of Fetal Alcohol Syndrome in Offspring of Chronically Alcoholic Women," [abstract] Pediatric Research 8 (1974): 166.
Acceptability and feadibility of early pregnancy termination
Home administration of misoprostol for a medical abortion is a safe and acceptable option for women in India, according to a study of women who chose medical abortion for early pregnancy termination
at clinics in New Dehli, Lucknow, Pune and Mumbai, between January 2007 and March 2008.
 In our case, patient had a similar presentation of heavy bleeding p/v following trial of an early pregnancy termination