eNOS

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eNOS

(ē'nos),

Abbreviation for endothelial nitric oxide synthase.

Farlex Partner Medical Dictionary © Farlex 2012

NOS3

A gene on chromosome 7q36 that encodes endothelial nitric oxide synthase (eNOS), a small molecule implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. eNOS is a critical mediator of cardiovascular homeostasis that regulates the diameter of blood vessels and keeps vascular proliferation and apoptosis in check. It is upregulated by dynamin, porin and soluble guanylyl cyclase, and downregulated by interactions with Hsp90 and Cav-1 in the Golgi and by NOSIP and NOSTRIN at the plasma membrane. NOS3 is also a less preferred gene symbol for what is now designated as NANOS3, see there.

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NOS3

References in periodicals archive ?

The results of the present study showed that rutin promoted NO production in HUVEC by inducing eNOS mRNA expression, protein synthesis, and eNOS activity.

Role of rutin on nitric oxide synthesis in human umbilical vein endothelial cells

The main results of meta-analysis for eNOS 4b/a polymorphism with the risk of DR were shown in Table 3.

Association between eNOS 4b/a polymorphism and the risk of diabetic retinopathy in type 2 diabetes mellitus: a meta-analysis

The aim of the present study was to investigate the possible association between eNOS 4a/b genotypes and alleles with the risk of preeclampsia.

Endothelial nitric oxide synthase (eNOS) 4a/b and G894T polymorphisms and susceptibility to preeclampsia

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HC seniors ready for Patriot League finals

eNOS inhibitor L-NA partially inhibited the effect of berberine on NO release.

Berberine protects against palmitate-induced endothelial dysfunction: involvements of upregulation of AMPK and eNOS and downregulation of NOX4

Then he sat in the toilet just staring at the light." The inmate said they told prison authorities and Enos was taken away for treatment.

Wife of dead prisoner may not get to husband's funeral

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Varying distribution of eNOS variants among ethnic groups may explain inter-ethnic differences in nitric oxide mediated vasodilation and response to drugs (28).

Endothelial nitric oxide synthase (eNOS) variants in cardiovascular disease: pharmacogenomic implications

The analysis of mean densitometric ratios of caveolin, Hsp90, and porin to eNOS protein respectively was performed by using NIH's Image J64 software (see URL above).

C-reactive protein adversely alters the protein-protein interaction of the endothelial isoform of nitric oxide synthase

eNOS generates NO in both vascular endothelial cells and platelets.

Expression and Activity of Platelet Endothelial Nitric Oxide Synthase Are Decreased in Patients with Coronary Thrombosis and Stenosis

The incumbent Byron-Bethany irrigation district director Larry Enos and challenger Milan 'Pete' Petrovich rolled the dice - taken from the board game of someone in the office - three times to determine the winner on Dec.