The most common Grade 1-2 adverse events were diarrhea, rash, thrombocytopenia, and dysgeusia
. 2 out of 7 patients experienced stable disease for greater than 6 months.
The most commonly observed side effects in controlled clinical studies, 5% or greater and at least 1.5 times placebo, include paraesthesia, dizziness, dysgeusia
, insomnia, constipation, and dry mouth.
The most common adverse reactions (>=20 %) with Rozlytrek were fatigue, constipation, altered sense of taste (dysgeusia
), swelling (edema), dizziness, diarrhea, nausea, nervous system disorders (dysesthesia), shortness of breath (dyspnea), muscle pain (myalgia), cognitive impairment, increased weight, cough, vomiting, fever (pyrexia), joint pain (arthralgia) and vision disorders.
The most commonly reported side effects of Rozlytrek include fatigue, constipation, dysgeusia
, edema, dizziness, diarrhea, nausea, dysesthesia, dyspnea, myalgia, cognitive impairment, weight gain, cough, vomiting, fever, arthralgia, and vision disorders.
(6) Toxicity (most commonly grade 1 and 2 dysgeusia
, muscle cramps, hair loss, and weight loss) led roughly half the patients to stop a continuous treatment regimen in the phase 2 trial.
Prophylactic administration of zinc or use of amifostine in the treatment of dysgeusia
has limited benefits and nutritional counselling is emphasized to help with dysgeusia
.23 Individuals mostly depend on vision and hearing and increasingly touch but unfortunately taste and smell are largely under-investigated and under-explored areas.
The most common adverse reactions associated with trastuzumab products in metastatic gastric cancer were neutropenia, diarrhea, fatigue, anemia, stomatitis, weight loss, upper respiratory tract infections, fever, thrombocytopenia, mucosal inflammation, nasopharyngitis, and dysgeusia
"I can't taste ice cream": an unusual case of tinnitus and dysgeusia
. Pediatr Emerg Care 2004; 20(12): 832-4.
The most common side effects included dissociation, nausea, vertigo, dysgeusia
(distortion of the sense of taste) and dizziness.
The most common acute toxicities were nausea and vomiting, mucositis, skin reaction due to radiation, xerostomia, dysphagia, and dysgeusia
. The grading was done according to the CTCAE criteria version 4.0.
Adverse events associated with IVIg treatment are generally mild and transient, such as headaches, erythema, and dysgeusia
. Potentially serious adverse events are uncommon and include acute tubular necrosis, aseptic meningitis or thrombotic complications.