dysgerminoma

(redirected from dysgerminomas)
Also found in: Dictionary, Encyclopedia.

dysgerminoma

 [dis-jer″mĭ-no´mah]
a solid, often radiosensitive, malignant ovarian neoplasm derived from undifferentiated germinal cells; the counterpart of seminoma of the testis.

dys·ger·mi·no·ma

(dis'jĕr-mi-nō'mă),
A malignant neoplasm of the ovary (counterpart of seminoma of the testis), composed of undifferentiated gonadal germinal cells and occurring more frequently in patients younger than 20 years of age. The neoplasms are grayish yellow and firm, contain foci of necrosis and hemorrhage, and tend to be encapsulated; characteristically, they spread by way of lymphatic vessels, but widespread metastases also occur.
Synonym(s): disgerminoma
[dys- + L. germen, a bud or sprout, + G. -ōma, tumor]

dys·ger·mi·no·ma

(dis'jĕr-mi-nō'mă)
A rare malignant neoplasm of the ovary composed of undifferentiated gonadal germinal cells and occurring more frequently in patients younger than 20 years of age. The neoplasms contain foci of necrosis and hemorrhage and tend to be encapsulated; characteristically, they spread by way of lymphatic vessels, but widespread metastases also occur.
[dys- + L. germen, a bud or sprout, + G. -ōma, tumor]
References in periodicals archive ?
MRI appearances of ovarian Dysgerminoma. European Journal of Radiology Extra.
Pregnancies complicated by dysgerminoma and Krukenberg tumour had favourable foetal outcome.
Histological examination of excised gonads in case 2 revealed features of an ovotestis with a gonadoblastoma and dysgerminomas in the left gonad and streak gonad parenchyma and PTH in the right gonad.
After operation, chemotherapy is suggested for all MGCTs excluding Stage I dysgerminoma or Stage I Grade 1 immature teratoma.
Treatment for early-stage dysgerminoma is surgical; young women should have at least unilateral oophorectomy performed; if the contralateral ovary is spared there's a 10% risk for recurrence over the next 2 years.
Likewise malignant germ cell tumours constituted the 2nd major category of ovarian cancers in Ashraf's study 38 comprising of 7 cases (15.56%), which included 3 cases of yolk sac tumours, 2 cases of dysgerminomas and 1 case each of mixed germ cell tumour and teratocarcinoma.
Dysgerminomas account for 1-5% of all ovarian malignancies in the first two decades of life.
Seminomas, dysgerminomas, and pancreatic adenocarcinomas are important and deadly tumors of humans and domestic animals.
A histopathological study of canine and feline ovarian dysgerminomas. Canad.
Dysgerminomas are unique among germ cell tumors because they are very sensitive to radiation therapy.
van de Geijn et al., "Prevalence of c-KIT mutations in gonadoblastoma and dysgerminomas of patients with disorders of sex development (DSD) and ovarian dysgerminomas," PloS one, vol.
(9) Dysgerminomas was noted between 17-23 years comparable to findings of Gault EW et al.