dysgerminoma


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dysgerminoma

 [dis-jer″mĭ-no´mah]
a solid, often radiosensitive, malignant ovarian neoplasm derived from undifferentiated germinal cells; the counterpart of seminoma of the testis.

dys·ger·mi·no·ma

(dis'jĕr-mi-nō'mă),
A malignant neoplasm of the ovary (counterpart of seminoma of the testis), composed of undifferentiated gonadal germinal cells and occurring more frequently in patients younger than 20 years of age. The neoplasms are grayish yellow and firm, contain foci of necrosis and hemorrhage, and tend to be encapsulated; characteristically, they spread by way of lymphatic vessels, but widespread metastases also occur.
Synonym(s): disgerminoma
[dys- + L. germen, a bud or sprout, + G. -ōma, tumor]

dysgerminoma

/dys·ger·mi·no·ma/ (-jer″mĭ-no´mah) a malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad; it is the counterpart of the classical testicular seminoma.

dysgerminoma

[dis′jərminō′mə] pl. dysgerminomas, dysgerminomata
Etymology: Gk, dys + L, germen, germ; Gk, oma, tumor
a rare malignant tumor of the ovary that occurs in young women and is believed to arise from the undifferentiated germ cells of the embryonic gonad. The tumor is histologically identical to seminoma. Dysgerminomas are extremely sensitive to irradiation and chemotherapy, and most patients retain their fertility. Also called embryoma of the ovary, ovarian seminoma.

dys·ger·mi·no·ma

(dis'jĕr-mi-nō'mă)
A rare malignant neoplasm of the ovary composed of undifferentiated gonadal germinal cells and occurring more frequently in patients younger than 20 years of age. The neoplasms contain foci of necrosis and hemorrhage and tend to be encapsulated; characteristically, they spread by way of lymphatic vessels, but widespread metastases also occur.
[dys- + L. germen, a bud or sprout, + G. -ōma, tumor]

dysgerminoma

a solid, often radiosensitive, malignant ovarian neoplasm derived from undifferentiated germinal cells; the counterpart of seminoma of the testis.
References in periodicals archive ?
OCT-4 is a reliable marker for both dysgerminoma and embryonal carcinoma.
Yolk sac tumors, immature teratomas and dysgerminomas are common components associated with embryonal carcinomas with all reported cases showing a mixed component.
Dysgerminomas are the most common malignant germ cell neoplasms, accounting for about one-third of cases.
To our knowledge, this is the first report of adrenal mixed GCT composed of dysgerminoma and embryonal carcinoma.
56%), which included 3 cases of yolk sac tumours, 2 cases of dysgerminomas and 1 case each of mixed germ cell tumour and teratocarcinoma.
A unique consideration in patients with dysgerminoma or choriocarcinoma is the possible diagnosis of XY gonadal dysgenesis, or Swyer syndrome.
The indications for the procedure include cervical cancer, lymphoma, unilateral ovarian dysgerminoma and rectal cancer.
Intestinal invasion by a dysgerminoma in a patient with Swyer syndrome.
Stuart's 40 year-old sister, an Army chaplain who was stationed in Iraq (2003-2004), developed Stage IV dysgerminoma, a rare ovarian germ cell cancer usually seen in teenage girls.
Among children and adolescents with complex adnexal masses, the most common neoplasm is a teratoma; the most common malignancy is a dysgerminoma.
Brewer M, Gershenson D, Herzog CE, Follen M, Silva EG, Taylor WJ (1999) Outcome and reproductive function after chemotherapy for ovarian dysgerminoma.