dyserythropoiesis

defective development of erythrocytes, such as anisocytosis and poikilocytosis.

dyserythropoiesis

Hematology Any defect of RBC production characterized by morphologic abnormalities of the nuclei and cytoplasm in the BM, which may be acquired–eg pernicious anemia, sideroblastic anemia, 2º to myeloproliferative disorders or erythroleukemia, or congenital–eg thalassemia, or congenital dyserythropoietic anemia. See Congenital dyserythropoietic anemia.

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Dyserythropoiesis has also been observed in a young patient with hereditary SA by Kyung et al from Korea15.

SIDEROBLASTIC ANEMIA-A HITHERTO UNRECOGNIZED CAUSE OF UNEXPLAINED ANEMIA

Tumour necrosis factor may contribute to the anemia of malaria by causing dyserythropoiesis and erythrophagoytosis.

HAEMATOLOGICAL ALTERATIONS ACCOMPANYING FALCIPARUM AND VIVAX MALARIA- A STUDY FROM A TERTIARY CARE TEACHING HOSPITAL IN NORTH-EAST INDIA

In evaluated patients with hemoglobin levels near normal ranges, correction of biologic markers of dyserythropoiesis was achieved.

Gene Therapy Found to Be Promising for ?-Thalassemia; CD34+ cells transduced with BB305 vector lowered or eliminated need for red-cell transfusions

Bone marrow biopsy was performed for pancytopenia and showed hypercellular bone marrow (80%) with erythroid hyperplasia and dyserythropoiesis. Flow cytometry showed polyclonal B-cells and plasma cells; no evidence of lymphoma was found.

Castleman's Disease and Posttransplant Lymphoproliferative Disorder after Liver Transplant: 3-Year Follow-Up

[beta]-TM is characterized by the absence or severe reduction of [beta]-globin chain production leading to globin chain imbalance, dyserythropoiesis, and severe anemia.

Understanding Iron Metabolism: Lessons from Transfusion-dependent Thalassemia

Malarial infections, particularly those associated with Plasmodium vivax, can cause both hemolysis (the destruction of red blood cells) and dyserythropoiesis (inadequate production of red blood cells) (Anstey et al.

Health and the Little Ice Age in Southeastern Germany and Alpine Austria: Synergies between Stress, Nutritional Deficiencies, and Disease

Bone marrow evaluation showed marked dyserythropoiesis. Case BIII.1 had mild microcytic anaemia, reticulocytosis, and increased ferritin levels; 17% of stomatocytes were detected at blood smear examination (Table 1 and Figure 2); the molecular testing for HBB gene revealed the presence of the splicing mutation c.93-21G>A at heterozygote level, confirming the beta-thalassemia trait.

Hereditary Xerocytosis due to Mutations in PIEZO1 Gene Associated with Heterozygous Pyruvate Kinase Deficiency and Beta-Thalassemia Trait in Two Unrelated Families

The most seriously affected were patients from Yugoslavia, showing hemolytic anemia, dyserythropoiesis, hepatosplenomegaly, and skeletal malformations [5, 7,11].

Biochemical and Molecular Analysis of the Hb Lepore Boston Washington in a Syrian Homozygous Child

(6,11) Myelodysplastic syndromes with inv(3)/t(3;3) typically present with decreased platelet counts with dysmegakaryopoiesis, dyserythropoiesis, and dysgranulopoiesis in 100%, 79.5%, and 71.8% of cases, respectively (Figure 1, A).

The New Clinicopathologic and Molecular Findings in Myeloid Neoplasms With inv(3)(q21q26)/t(3;3)(q21;q26.2)

Red cell inclusions result from oxidant stress, severe infections and dyserythropoiesis (maturation defects).

Morphologic evaluation of Anemia--I

Malaria-related dyserythropoiesis (14) might be less pronounced in African patients than in European patients.

Hemolysis after oral artemisinin combination therapy for uncomplicated plasmodium falciparum malaria

showed that bone marrows which were stained within 24 hours did not show marked discernible dyserythropoiesis.15