dyserythropoiesis

dyserythropoiesis

 
defective development of erythrocytes, such as anisocytosis and poikilocytosis.

dyserythropoiesis

Hematology Any defect of RBC production characterized by morphologic abnormalities of the nuclei and cytoplasm in the BM, which may be acquired–eg pernicious anemia, sideroblastic anemia, 2º to myeloproliferative disorders or erythroleukemia, or congenital–eg thalassemia, or congenital dyserythropoietic anemia. See Congenital dyserythropoietic anemia.
References in periodicals archive ?
Dyserythropoiesis has also been observed in a young patient with hereditary SA by Kyung et al from Korea15.
Tumour necrosis factor may contribute to the anemia of malaria by causing dyserythropoiesis and erythrophagoytosis.
In evaluated patients with hemoglobin levels near normal ranges, correction of biologic markers of dyserythropoiesis was achieved.
Bone marrow biopsy was performed for pancytopenia and showed hypercellular bone marrow (80%) with erythroid hyperplasia and dyserythropoiesis. Flow cytometry showed polyclonal B-cells and plasma cells; no evidence of lymphoma was found.
[beta]-TM is characterized by the absence or severe reduction of [beta]-globin chain production leading to globin chain imbalance, dyserythropoiesis, and severe anemia.
Malarial infections, particularly those associated with Plasmodium vivax, can cause both hemolysis (the destruction of red blood cells) and dyserythropoiesis (inadequate production of red blood cells) (Anstey et al.
Bone marrow evaluation showed marked dyserythropoiesis. Case BIII.1 had mild microcytic anaemia, reticulocytosis, and increased ferritin levels; 17% of stomatocytes were detected at blood smear examination (Table 1 and Figure 2); the molecular testing for HBB gene revealed the presence of the splicing mutation c.93-21G>A at heterozygote level, confirming the beta-thalassemia trait.
The most seriously affected were patients from Yugoslavia, showing hemolytic anemia, dyserythropoiesis, hepatosplenomegaly, and skeletal malformations [5, 7,11].
(6,11) Myelodysplastic syndromes with inv(3)/t(3;3) typically present with decreased platelet counts with dysmegakaryopoiesis, dyserythropoiesis, and dysgranulopoiesis in 100%, 79.5%, and 71.8% of cases, respectively (Figure 1, A).
Red cell inclusions result from oxidant stress, severe infections and dyserythropoiesis (maturation defects).
Malaria-related dyserythropoiesis (14) might be less pronounced in African patients than in European patients.
showed that bone marrows which were stained within 24 hours did not show marked discernible dyserythropoiesis.15