dyscrasia


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dyscrasia

 [dis-kra´zhah]
a condition related to a disease or pathologic state, usually referring to an imbalance of component elements. adj., adj dyscrat´ic.
blood dyscrasia a pathologic condition of the blood, usually referring to a disorder of the cellular elements of the blood.
plasma cell d's a diverse group of neoplastic diseases involving proliferation of a single clone of cells producing a serum M component (a monoclonal immunoglobulin or immunoglobulin fragment); the cells usually have plasma cell morphology, but may have lymphocytic or lymphoplasmacytic morphology. The group includes multiple myeloma, Waldenström's macroglobulinemia, the heavy chain diseases, benign monoclonal gammopathy, and immunocytic amyloidosis. Called also paraproteinemias and monoclonal gammopathies.

dys·cra·si·a

(dis-krā'zē-ă),
1. A morbid general state resulting from the presence of abnormal material in the blood, usually applied to diseases affecting blood cells or platelets.
2. Old term indicating disease.
[G. bad temperament, fr. dys- + krasis, a mixing]

dyscrasia

(dĭs-krā′zhə, -zhē-ə)
n.
An abnormal bodily condition, especially of the blood.

dyscrasia

See Blood dyscrasia, Plasma cell dyscrasia, Plasma cell dyscrasia with polyneuropathy.

dys·cra·si·a

(dis-krā'zē-ă)
Any morbid general state resulting from the presence of abnormal material in the blood, usually applied to diseases affecting blood cells or platelets.
[G. bad temperament, fr. dys- + krasis, a mixing]

dyscrasia

A vague term meaning any abnormal condition of the body.

dys·cra·si·a

(dis-krā'zē-ă)
Morbid general state resulting from presence of abnormal material in blood.
[G. bad temperament, fr. dys- + krasis, a mixing]
References in periodicals archive ?
Distribution of Pathology-Driven Algorithmic Testing Cases (a) Patients on Patients on Malignant Track Each Track 2 Tracks Diagnosis PSRs Acute leukemia 26 0 26 25 Treated acute leukemia 66 1 0 0 Cytopenias 58 10 18 9 CML 3 0 3 2 MPN 39 0 29 19 Plasma cell dyscrasia 46 3 34 21 Lymphoma 89 5 42 9 Other 7 1 0 0 Total 334 10 (b) 152 85 New PSRs on Malignant New Diagnoses, Track Diagnosis No.
Talley, "Plasma-cell dyscrasia with polyneuropathy.
(3) There is an absence of related organ or tissue impairment due to plasma cell dyscrasias, such as renal failure or anaemia, and normal calcium levels.
Closer monitoring should be applied to clozapine recipients with a history of blood dyscrasia. The combination of clozapine and other potentially leukopenic drugs, especially sodium valproate, should be limited.
We report five patients with plasma cell dyscrasia, four had C3GP and one had DDD proven by kidney biopsies.
Most commonly it is indicated pre- or post-operatively in building-up and making up the loss; in blood loss such as accidents and surgical operations; blood disorders such as hemophilia, purpura, clotting defect; and blood diseases such as severe anemia, leukemia, and blood dyscrasia.
In addition, monoclonal T cells have been found in some cases of PLC and many cases of PLEVA, suggesting that the disorders, though not true cutaneous T cell lymphomas, represent inflammatory reactions to an underlying T cell dyscrasia.4,5
POEMS syndrome is a underlying plasma cell dyscrasia related paraneoplastic syndrome and CD is one of the major criteria in the diagnosis of this disease.
What type of plasma cell dyscrasia is associated with these results?
MTH is a well tolerated drug, but it requires regular checkup of complete blood count and liver function before the initiation of therapy and during the treatment in order to avoid blood dyscrasia and hepatotoxicity.
In addition, SLE and SS are also associated with some plasma cell dyscrasias, such as monoclonal gammopathy of undetermined significance, macroglobulinemia, and amyloidosis; however, multiple myeloma (MM) as a lymphoproliferative neoplasm and plasma cell dyscrasia are not nearly as common.
Clinical Approach to a Patient with Plasma Cell Dyscrasia about to Undergo Radiocontrast Studies