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en·chon·dro·ma·to·sis(en-kon'drō-ma-tō'sis), [MIM*166000 *225795]
A rare disorder characterized by hamartomatous proliferation of cartilage in the metaphyses of several bones, most commonly of the hands and feet, causing distorted growth in length and pathologic fractures; chondrosarcoma may develop. When enchondromatosis is associated with hemangiomas in the cutaneous or visceral regions, the condition is called Maffucci syndrome. Most cases are sporadic but a few instances demonstrate autosomal dominant inheritance with reduced penetrance.
Synonym(s): asymmetric chondrodystrophy, dyschondroplasia, hereditary deforming chondrodystrophy (2) , Ollier disease
Farlex Partner Medical Dictionary © Farlex 2012
dyschondroplasia(1) A nonspecific term for any defect in chondrogenesis that extends into the metaphysis and diaphysis.
(2) Enchondromatosis, see there.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
A rare familial, and probably hamartomatous, proliferation of cartilage in the metaphyses of several bones, most commonly of the hands and feet, causing distorted growth in length or pathologic fractures; chondrosarcoma frequently develops. When combined with hemangiomas in the cutaneous or visceral regions, it is called Maffucci syndrome.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
dyschondroplasiaA rare progressive disease of the growing parts of bone (epiphyses), affecting children and causing growth retardation. The bones of the limbs are abnormally short, often unequal, and show nodular swellings.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005