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(dĭs″bī-ō′sĭs) [″ + Gr. biosis, living]
An unhealthy change in the normal bacterial ecology of a part of body, e.g., of the intestines or the oral cavity.


The condition that results when the natural flora of the gut are thrown out of balance, such as when antibiotics are taken.
Mentioned in: Colonic Irrigation

dysbiosis (dis·bē·ōˑ·sis),

n an imbalance in the intestinal bacteria that precipitates changes in the normal activities of the gastrointestinal tract or vagina, possibly resulting in health problems. Also called
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References in periodicals archive ?
Her dietary intake included red meat 3 times a week and a regular high intake of leafy greens, fruit and vegetables, which may have meant a sufficient intake of iron and B12; however, Kate has a higher demand for these nutrients due to the levels of inflammation associated with MS9 and a possible reduction of B12 absorption in the small intestine, which can occur with diarrhoea and dysbiosis.
3) Secondary candidiasis is common and is usually associated with immune system suppression (eg, neonates, stress, overcrowding), concurrent disease (eg, hypovitaminosis A, malnutrition), prolonged broad-spectrum antibiotic therapy, or other causes of dysbiosis.
It is clear that new diagnostic solutions are needed to properly address the growing problem of antibiotic-induced dysbiosis and associated hospital-acquired bacterial infections, stated Pierre Belichard, CEO of Enterome.
This is despite the four proposed pathogenic causes of UC: dysbiosis, inflammation, impaired immunoregulation, and impaired mucosal functioning [19], all occurring in many settings of critical illness.
Overall, because infants might be vulnerable to community disruptions and dysbiosis, we recommend that new trials, such as studies on efficacy of broader pneumococcal coverage vaccines, consider the effect of vaccination on the commensal flora in its totality instead of only on a single species.
Exposure to antibiotics may somehow contribute to alterations in the microbiome and result in dysbiosis, which is known to be part of the pathogenesis that leads to IBD," said Dr.
Cancer patients also exhibit shifts in the composition of their gut microbiota - a phenomenon called dysbiosis - but it's unclear whether changes in the microbiome drive the development of cancer or the cancer drives changes in the microbiome.
Although their etiology and pathophysiology are still unclear, an impaired intestinal barrier function, dysbiosis (an imbalance in the intestinal bacterial ecosystem) and immunologic mechanisms have been advocated an important role (Dotan and Mayer, 2002; Melmed and Abreu, 2004; Hanauer, 2006; Shaw et al.
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.
The result of this is oral dysbiosis, increased dental caries and gum disease and increased upper respiratory infection.
However, there are many conditions that can contribute to dysbiosis (unhealthy balance of gut flora) such as severe Candida albicans, parasites, heavy metal toxicity and use of chemotherapy, antibiotics and other drugs.
An imbalance between protective and harmful bacteria, also called dysbiosis, is, for the most part, responsible for the rising incidence of IBD.