dye exclusion test

dye ex·clu·sion test

a test to determine cell viability in which a dilute solution of certain dyes (for example, trypan blue, eosin Y, nigrosin, Alcian blue) is mixed with a suspension of live cells; cells that exclude dye are considered to be alive whereas cells that stain are considered dead; it is not always an accurate test because it indicates only the structural integrity of the cell membrane.
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It is interesting to note that there was a discrepancy in the [IC.sub.50] value achieved from MTT and trypan blue dye exclusion test (Table 1).
THE IC50 VALUE OF MCF-7 AND MOLT-4 CELLS TREATED WITH NORDAMNACANTHAL FOR 72 HOURS AS DETERMINED USING MTT ASSAY AND TRYPAN BLUE DYE EXCLUSION TEST. Each sample was run in triplicate.
It failed to exhibit cytotoxic action on PMNL as revealed by the dye exclusion test or irritant effect on rabbit cornea.