duration of action


Also found in: Acronyms.

duration of action

Therapeutics The length of time that a particular drug is effective

du·ra·tion of ac·tion

(dŭr-ā'shŭn ak'shŭn)
The amount of time that a measurable drug effect persists.
References in periodicals archive ?
The investigators are interested in repeating their investigation with liposomal bupivacaine (Exparel), which has a duration of action past 24 hours.
[7] Similarly, intraarticular clonidine following arthroscopic knee surgery [8-10] has been shown to prolong the duration of action of local anaesthetics [11] as well as to selectively block the conduction of A d and C fibres.
Ease of administration, long duration of action, and a great taste are all positive attributes.
Conclusion: It was observed in our clinical trial that body weight calculation and dosage of atracurium accordingly has altered duration for recovery from blockade, the results of the study showed that atracurium when used according to ideal body weight as compared to total body weight has reduced duration of action. So atracurium dose should be calculated according to ideal body weight rather than total body weight in obese patients.
In June 2017, long-acting, triple-bead mixed amphetamine salt (MAS) was FDA-approved under the brand name Mydayis for the once-daily treatment of ADHD in adolescents (age [greater than or equal to]13) and adults (Table l).3 This formulation utilizes a unique triple-bead technology to extend its duration of action. When this technology was developed-nearly a decade ago--it was hoped that the duration of action of the stimulant would be significantly increased, beyond the 10- to 12-hour duration of action of available stimulants at that time.
Rocuronium is a steroidal nondepolarizing muscle relaxant with duration of action ranging from 38 to 150 mins [8].
This insulin will give diabetics a chance to feel safe and remove worries in their minds." Tresiba provides an ultra-long duration of action beyond 42-hours allowing for flexibility in day-to-day dosing time when needed, without compromising efficacy or risk of hypoglycaemia."It is more flexible since patients can take it at any time of the day.
Rocuronium bromide, ORG-9246, a newer nondepolarizing muscle relaxant with quick onset and intermediate duration of action has one-sixth of potency of vecuronium, which was introduced in the 1990s.
Limitations, however, relate to their prolonged half-life and duration of action. Once in the system an injected or ingested drug cannot be taken out.
It is said to provide a long duration of action (beyond 42 hours).
It combines the best features of the other two: lidocaine's rapid onset along with a duration of action that's even longer than bupivacaine's, she noted.
Adding solar power improves duration of action and average speed such that magnetohydrodynamic propulsion may be an important force for liquid propulsion in the future.