duration of action


Also found in: Acronyms.

duration of action

Therapeutics The length of time that a particular drug is effective

du·ra·tion of ac·tion

(dŭr-ā'shŭn ak'shŭn)
The amount of time that a measurable drug effect persists.
References in periodicals archive ?
Conclusion: It was observed in our clinical trial that body weight calculation and dosage of atracurium accordingly has altered duration for recovery from blockade, the results of the study showed that atracurium when used according to ideal body weight as compared to total body weight has reduced duration of action.
When this technology was developed-nearly a decade ago--it was hoped that the duration of action of the stimulant would be significantly increased, beyond the 10- to 12-hour duration of action of available stimulants at that time.
4] did a comparable evaluation of intubating conditions, onset of action, and duration of action of rocuronium bromide and vecuronium bromide.
The duration of action exceeded 25mins in the rest of the patients in both groups.
Organized by drug class, it provides bulleted information on classification, definitions, product availability, indications, and other general comments; pharmacology, pharmacological and psychiatric effects, dosing, pharmacokinetics, onset and duration of action, and switching and augmentation strategies; adverse effects, contraindications, discontinuation syndrome, precautions, toxicity, and food and drug interactions; and patient-related issues like lab tests and monitoring, use in pregnancy, nursing implications and treatment, and patient instructions.
Insulin can be classified as short-acting, premixed and basal, depending upon their duration of action.
With sections organized by drug type, it contains general information on drugs and treatment, including their classification, definition, indications, and availability; drug action and dosing information, including pharmacology, pharmacological and psychiatric effects, pharmacokinetics, onset and duration of action, and switching and augmentation strategies; warnings and precautions such as adverse effects, contraindications, discontinuation syndrome, precautions, toxicity, and food and drug interactions; and patient-related information such as lab tests and monitoring, pediatric and geriatric considerations, uses in pregnancy, medicolegal issues, nursing implications and treatment, and patient instructions.
Only four stimulants are approved by the Food and Drug Administration for adults: Adderal XR (dextroam-phetamine/amphetamine), with a 9-hour duration of action and 15- to 30-mg dosage range; Focalin XR (dexmethylphenidate), with an 8- to 12-hour duration of action and dosage range of 20-40 mg; Vyvanse (lisdexamfetamine dimesylate), with a duration of 12 hours and dosing at 30-70 mg; and Concerta (methylphenidate extended-release), with a 12-hour duration of action and dosage range of 18-54 mg.
We too have used this combination of drugs for ECT in a 60-year-old male with prolonged duration of action of succinylcholine but normal plasma cholinesterase levels, who later turned out to be heterozygous for the atypical variant of cholinesterase.
The intubating conditions, onset of action, duration of action, haemodynamic changes and side effects of the studied drugs were observed.
EoACA[pounds sterling]The long duration of action of both components of TWYNSTAEeA make it a unique and very meaningful option in the treatment of hypertension where blood pressure control is not achieved with monotherapy alone.