The glycosylases known to repair [o.sup.8]G in duplex DNA
, such as OGG1, NEIL1, and NEIL3, cannot remove [o.sup.8]G from DNA GQs, although these enzymes do repair guanidinohydantoin and spiroiminodihydantoin in GQs .
This is because the 6-heterocycles stack with their neighboring natural bases in the duplex DNA
. However, the nucleoside derivatives of v are chemically less stable under basic conditions, relative to those of s.
Minor groove binders are a potent class of naturally occurring antibiotics that bind to duplex DNA
specifically in the minor groove.
Binding of Oxovanadium ions to the major and minor groove of duplex DNA
: stability and structural models.
replication, the duplex DNA
splits apart, with each old strand becoming
Actinomycin D has been shown to preferentially bind to dGpC steps of duplex DNA
, and more recently atypical binding sites such as the T(G) nT motif.
of Basel, Switzerland) here presents nine articles on important aspects of charge transfer processes in DNA, including the principles and mechanisms of photoinduced charge injection, transport, and trapping in DNA; sequence-dependent dynamics as the regulator of DNA-mediated charge transport; excess electron transfer in DNA probed with flavin- and thymine dimmer-modified oligonucleotides; dynamics of photoinitiated hole and electron injection in duplex DNA
; spectroscopic investigation of charge transfer in DNA; and electron transfer and structural dynamics in DNA.
Polymerases catalyze accurate multiplication and maintenance of genomes and helicases which accomplish unwinding of duplex DNA
are some of the other enzyme systems which are present in the organisms.
Recognition of base J in duplex DNA
by J-binding protein.
Our research objective was to form a stable triplex structure within a mismatched region of duplex DNA
. The results show that DNA formed in the presence of coralyne at high salt concentration increases duplex DNA
stability as indicated by significant increases in duplex melting temperature with increased salt concentrations.