duodenal ulcer

Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.


a local defect, or excavation of the surface of an organ or tissue, produced by sloughing of necrotic inflammatory tissue.
aphthous ulcer a small painful ulcer in the mouth, approximately 2 to 5 mm in diameter. It usually remains for five to seven days and heals within two weeks with no scarring.
chronic leg ulcer ulceration of the lower leg caused by peripheral vascular disease involving either arteries and arterioles or veins and venules of the affected limb. Arterial and venous ulcers are quite different and require different modes of treatment. Venous stasis ulcers occur as a result of venous insufficiency in the lower limb. The insufficiency is due to deep vein thrombosis and failure of the one-way valves that act during muscle contraction to prevent the backflow of blood. Chronic varicosities of the veins can also cause venous stasis.

Patient Care. Stasis ulcers are difficult to treat because impaired blood flow interferes with the normal healing process and prolongs repair. Patient care is concerned with preventing a superimposed infection in the ulcer, increasing blood flow in the deeper veins, and decreasing pressure within the superficial veins.
decubitus ulcer pressure ulcer.
duodenal ulcer an ulcer of the duodenum, one of the two most common types of peptic ulcer.
gastric ulcer an ulcer of the inner wall of the stomach, one of the two most common kinds of peptic ulcer.
Hunner's ulcer one involving all layers of the bladder wall, seen in interstitial cystitis.
hypertensive ischemic ulcer a manifestation of infarction of the skin due to arteriolar occlusion as part of a longstanding vascular disease, seen especially in women in late middle age, and presenting as a red painful plaque on the lower limb or ankle that later breaks down into a superficial ulcer surrounded by a zone of purpuric erythema.
marginal ulcer a peptic ulcer occurring at the margin of a surgical anastomosis of the stomach and small intestine or duodenum. Marginal ulcers are a frequent complication of surgical treatment for peptic ulcer; they are difficult to control medically and often require further surgery.
peptic ulcer see peptic ulcer.
perforating ulcer one that involves the entire thickness of an organ, creating an opening on both surfaces.
phagedenic ulcer
1. any of a group of conditions due to secondary bacterial invasion of a preexisting cutaneous lesion or the intact skin of an individual with impaired resistance as a result of a systemic disease, which is characterized by necrotic ulceration associated with prominent tissue destruction.
pressure ulcer see pressure ulcer.
rodent ulcer ulcerating basal cell carcinoma of the skin.
stasis ulcer ulceration on the ankle due to venous insufficiency and venous stasis.
stress ulcer a type of peptic ulcer, usually gastric, resulting from stress; possible predisposing factors include changes in the microcirculation of the gastric mucosa, increased permeability of the gastric mucosa barrier to H+, and impaired cell proliferation.
trophic ulcer one due to imperfect nutrition of the part.
tropical ulcer
1. a lesion of cutaneous leishmaniasis.
tropical phagedenic ulcer a chronic, painful phagedenic ulcer usually seen on the lower limbs of malnourished children in the tropics; the etiology is unknown, but spirochetes, fusiform bacilli, and other bacteria are often present in the developing lesion, and protein and vitamin deficiency with lowered resistance to infection may play a role in the etiology.
varicose ulcer an ulcer due to varicose veins.
venereal ulcer a nonspecific term referring to the formation of ulcers resembling chancre or chancroid about the external genitalia; there are both sexually transmitted and other types.

duodenal ulcer

an ulcer of the duodenum; 90% associated with Helicobacter pylori infection.
See also: peptic ulcer.

duodenal ulcer

an ulcer in the duodenum, the most common type of peptic ulcer. See also peptic ulcer.

duodenal ulcer

An ulcer of the duodenum Epidemiology H pylori infection of stomach, NSAIDs and other anti-inflammatory agents, and cigarettes Clinical Pain, often post-prandial which may not correlate with presence or severity of ulcers Diagnosis Barium swallow, endoscopy Complications Bleeding, perforation, gastric obstruction Management Antibiotics–eg, amoxicillin, metronidazole   to eradicate H pylori, ↓ risk factors, prevent complications

du·o·de·nal ul·cer

(dūō-dēnăl ŭlsĕr)
Lesion of the duodenum; about 90% associated with Helicobacter pylori infection.

duodenal ulcer

A crater in the lining of the first part of the small intestine (the DUODENUM) usually caused by the action of strong acid and digestive enzymes coming from the stomach. Duodenal ulcer is also related to the presence of an organism Helicobacter pylori . Destruction of this organism with antibiotics, together with the use of proton pump inhibitor drugs such as OMEPRAZOLE (Losec), has been shown to cure many ulcers and to prevent recurrence. See also PEPTIC ULCER.

duodenal ulcer,

n a peptic ulcer located in the duodenum. See also ulcer, peptic.


of or pertaining to the duodenum.

duodenal glands
glands in the submucosa of the duodenum, opening into the small intestine; called also Brunner's glands.
duodenal reflux
retrograde movement of duodenal contents, either into the stomach where it has been incriminated as a cause of vomiting and gastric hyposecretion, or into the pancreatic duct and parenchyma as a factor in the etiology of acute pancreatitis.
duodenal stenosis
occurs in young foals up to 4 months old. Characterized by salivation, mild colic, regurgitation and unthriftiness.
duodenal ulcer
peptic ulcer of the duodenum. See also ulcer.

Patient discussion about duodenal ulcer

Q. What is the difference between duodenal ulcer and stomach ulcer? I was diagnosed recently with duodenal ulcer. I heard the term stomach ulcer but not duodenal. What causes duodenal and what cause stomach ulcer? And how do they treat duodenal ulcer?

A. The duodenum is right after the stomach. They are both (as published a few years back) caused 90% of the time from a bacteria named helicobacter pylori. Hence the treatment for it is probably antibiotics. But I guess that should be your doctor’s call. Good luck!

More discussions about duodenal ulcer
References in periodicals archive ?
pylori was present at a high ratio in the antral biopsies of patients with duodenal ulcer perforation.
Devise corrective measures for pipeline projects by understanding Duodenal Ulcer pipeline depth and focus of Indication therapeutics.
Factors influencing mortality in perforated duodenal ulcer following emergency surgical repair.
Duodenal ulcer is a chronic acid peptic disease, with frequent remissions and relapses with and without treatment1.
granatum fruit has been studied against various models of experimentally induced gastric and duodenal ulcer in order to evaluate its mechanism of action involved in prevention of ulcer formation.
Incidence of duodenal ulcer perforation in patients on anti-ulcer therapy.
By day 7, only 7% of patients in the celecoxib group had gastric and/or duodenal ulcers, compared with 25% of those in the naproxen group and 2% of those in the placebo group.
Dear Miriam MY husband recently had an endoscopy and was told he has two duodenal ulcers.
Sixteen of the children had severe GI bleeding, two had perforated duodenal ulcers that required surgery, and seven had to be hospitalized for several days for severe abdominal pain, she said in an interview.