PDE4C

(redirected from dunce)
Also found in: Dictionary, Thesaurus, Legal, Acronyms, Idioms, Wikipedia.

PDE4C

A gene on chromosome 19p13.11 that encodes a nucleotide phosphodiesterase, which plays a critical role in signal transduction by hydrolysing the second messenger cAMP to AMP or cGMP to GMP; it thereby plays a role in regulating physiological processes, including vascular proliferation and contraction, cardiac contractility, platelet aggregation, hormone secretion and immune cell activation.
References in periodicals archive ?
LEADING RESULTS - Men: 1 M Fenwick (TyneBr) 31:30; 2 J Dunce (TyneBr) 31:54; 3 F Brodie (TyneBr) 32:01; 4 A Bailes (Birt) 32:05; 5 T Charlton (TyneBr) 32:54; 6 R Eaton (DurC) 33:02; 7 G Wallace (BhillBnds) 33:13; 8 S Ellis (NSP) 33:29; 9 M Hedley (JesJog) 33:31; 10 I Ritchie (Sund) 33:43.
Suddenly, the worn-out schoolboy dropped from being one of the school's brightest pupils to one of its biggest dunces.
Dubliner Diarmuid said: "I was the family dunce and my parents were very worried about me.
ROBERT PIRES goes into today's Confederations Cup Final admitting to being a lazy dunce at school.
I called him stupid, a dunce and said he needed to go to a special school, " said Mr Wheatley.
I take back everything Iive ever said about bingo being for clapped out dunce brains.
This causes some very uncompelling friction - Matt (Saget) shares with his classes benignly embarrassing information about his daughter, Sarah (Kat Dennings), who frets and fumes and berates him, only for the poor dunce to go and reveal something else.
WHEN they thought of class, Britney was outside waiting for the headmaster with a dunce cap on.
Jesse Ventura, the ex-wrestler and actor who proves that an amiable, charismatic dunce can indeed go far in talk show politics.
AN obliging St Johnstone jobsworth told us the official attendance was 2067 but it's odds-on he was the school dunce at arithmetic.
Who is the biggest dunce is the question that needs answering.
They should have been sent to the corner with dunce caps on their heads.