PDE4C

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PDE4C

A gene on chromosome 19p13.11 that encodes a nucleotide phosphodiesterase, which plays a critical role in signal transduction by hydrolysing the second messenger cAMP to AMP or cGMP to GMP; it thereby plays a role in regulating physiological processes, including vascular proliferation and contraction, cardiac contractility, platelet aggregation, hormone secretion and immune cell activation.
References in periodicals archive ?
As of March 20, the man behind the word dunce is now officially a "blessed" of the church.
His opposition to classical studies led in the Renaissance to the use of his name (Duns, Dunse, or Dunce) for a pedantic sophist incapable of real learning, and thence to the current meaning of dunce
James Dunce (Tyne Bridge) set the early pace ahead of Morpeth duo Scott Beattie and Ross Floyd and Sunderland's Kevin Calvert and Sean Hall of Gateshead.
Duncan Dunce, principal analyst at Flexlife, said: "It's great to have the opportunity to raise funds for Monty's Maggie's appeal, to help support the work they do and contribute to the development of centres in Newcastle and Aberdeen.
For example, the Drosophila gene known as dunce, which Davis helped identify several years ago, provided clues to the genetics of the devastating psychiatric condition of schizophrenia.
The Chancellor, who is itching to start his own education revolution, will effectively be awarding Mr Blair a dunce's E after almost 10 years of school, college and university reforms.
He was by no means the dunce of the class; another hapless flyer slammed into our bridge.
ZOE regained her crown as Strictly Come Dancing favourite last night - as dance-floor dunce Fiona Phillips was booted off.
Go to the bottom of the class, professor Drummond Bone vice-chancellor and chief executive of Liverpool University, had to don the dunce's cap when he gave this year's Adrian Henri State of the Arts memorial lecture.
The runners up were THE CLOWN JEWELS from David Turvey of Marston Green and RIVER DUNCE from Mr M Wilson of Halesowen.
The vision of a mentally disabled patient dressed as a ghost with a skeleton mask, or of a couple in a dunce, hat and clown suit holding hands on a wide lawn under a dark somber sky, looks like Grimm's fairy tales.
Last week's Heaton Memorial 10k winner Marc Fenwick was among the chasing pack, together with his Tyne Bridge team-mate James Dunce, the promoting club's Chris Steele, Keswick's Sam Stead, Marc Brown (Salford) and Trafford's James Bowness.