(a) The picture of the neoforming oval cell ductule
. Two HPCs (HPC I, HPC II) form the growing bile ductule
in a close vicinity of the limiting plate of the hepatic lobule.
In the region defined caput are including small efferent ductules
with ciliate cubic epithelium that does not change during the year .
(76) In typical cases, ductular reaction is prominent and consists of a proliferation of small, interanastomosing ductules
located at the periphery of the portal tracts.
Epithelial-myoepithelial carcinomas are biphasic tumors, which largely recapitulate intercalated ductule
Focally, islet cells and ductules
were intermixed (Figure 1).
Estrogen involves in regulation of male reproduction, including the function of Sertoli and Leydig cells in the testis and sperm maturation in the efferent ductules
and epididymis [23, 25].
After giving birth, breast lobules switch to a secretory phenotype and ductules
are found to be dilated.
This primary bile is then modified along ductules
and ducts by absorptive and secretory processes that take place in the cholangiocyte epithelium .
Ductular reaction consists in proliferation of small interanastomosing ductules
located at the periphery of portal tracts and represents the most consistent indicator of the presence of biliary obstruction .
sicula-untreated males, IHC investigations showed that only the corpus appeared devoid of ER[alpha] immunoreactivity, while the efferent ductules
and cauda were positive to ir-Er[alpha] signal (Figure 3(f)).
Bile duct ligation (BDL), a commonly used rat model of liver fibrosis, stimulates the proliferation of biliary epithelial cells and oval cells resulting in proliferating bile ductules
and an accompanying portal inflammation, fibrosis, and a secondary biliary cirrhosis, similar to that of humans.
(126, 127) Glutamine synthetase is usually not expressed in hepatocytes around fibrous scars containing arteries and bile ductules
. This unique "maplike" pattern is seen in virtually all FNH cases, including those that are morphologically uncharacteristic (Figure 6, A).