dual reuptake inhibitor


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Related to dual reuptake inhibitor: Serotonin reuptake inhibitor

dual reuptake inhibitor

An antidepressant medication that works by blocking the reuptake of both serotonin and norepinephrine.
See also: inhibitor
References in periodicals archive ?
There are two other dual reuptake inhibitors: venlafaxine (at higher doses) and the experimental drug milnacipran, which is being developed in the United States for the treatment of fibromyalgia but is available in France and Japan.
However, the most prescribed classes of drugs in the therapy of depression remain the selective serotonin reuptake inhibitors and the dual reuptake inhibitors of serotonin and norepinephrine, even if part of the data asserts that only 50% of the patients treated with one of these two classes show proof of clinical remission (2).
Far more effective for fibromyalgia - and most likely other central pain states as well - are dual reuptake inhibitors such as tricyclic compounds (amitriptyline, cyclobenzaprine), serotonin-norepinephrine reuptake inhibitors (milnacipran, duloxetine), gamma hydroxybutyrate, and gabapentin.

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