PDE11A(redirected from dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A)
PDE11AA gene on chromosome 2q31.2 that encodes a cyclic nucleotide phosphodiesterase, which hydrolyses cAMP to 5’-AMP and cGMP to 5’-GMP, downregulating cAMP and cGMP signalling.
PDE11A mutations may cause Cushing disease and adrenocortical hyperplasia.
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