drugs


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drugs

pharmacophobia.

hypohidrosis

Reduced sweat production
Hypohidrosis
I Inherited conditions, eg hereditary anhydrotic ectodermal dysplasia, ichthyosis, or angiokeratoma corporis diffusum universale
II Acquired conditions
 Collagen vascular diseases–-Sjögren syndrome, progressive systemic sclerosis
 Dermatopathies–Miliaria profunda, pemphigus vulgaris, psoriasis
 Drugs Anticholinergics, eg atropine, scopolamine; ganglionic blockers
 Endocrinopathies Diabetes insipidus, hypothyroidism, hypothalamic lesions
 Environmental stress Heat stroke and dehydration
Peripheral neuropathy Alcohol, amyloidosis, DM, Horner syndrome, leprosy  

gynecomastia

Benign enlargement of ♂ breast that most commonly affects boys and adolescents, often regresses at puberty; it is usually due to a proliferation of glandular component; may occur in Klinefelter syndrome or after malnutrition Age-related peaks
1. Perinatal, in 60-90% of ♂ at birth, due to transplacental passage of estrogens.
2. Pubertal, up to 70%, depending on stringency of definition.
3. Involutional, age 50-80% Treatment Clomiphene, tamoxifen, testolactone, surgery. See Adolescent gynecomastia.
Gynecomastia Etiology
Endocrinopathy Orchitis, hypogonadism–androgen deficiency, androgen resistance, tumors/hyperplasia of adrenal gland, testes, eg Leydig cell tumor–↑ hCG, lung CA, Klinefelter syndrome–↑ risk of breast CA and thyroid hyperplasia
Drugs α-methyldopa, amphetamine, androgens, benzodiazepines, cimetidine, chemotherapeutics, digitalis, INH, marijuana, penicillamine, phenothiazine, reserpine, spironolactone, tricyclic antidepressants
Other conditions Starvation diet–mechanism: testicular, hepatic hypofunction or on resuming feeding, hemodialysis, liver disease–cirrhosis, hepatomas, hemochromatosis, due to ↓ hepatic metabolism of estrogens, mycosis fungoides, myotonic dystrophy with spastic paraplegia, leprosy
.
References in periodicals archive ?
Drug companies, editorialized the paper, "toss out several unconvincing arguments against allowing Medicare to negotiate with them.
Controlling the channel of distribution: Plan sponsors have found that limiting the size of pharmacy networks used to dispense specialty drugs can significantly reduce costs.
Excluding alcohol, tobacco, marijuana, and cocaine, for which drugs is it most important to develop supplementary prevention materials for seventh and eighth graders?
The employee could be abusing illegal drugs or under a doctor's care, taking a prescription drug.
To the Editor: Global surveillance of drug resistance has shown that a substantial proportion of tuberculosis (TB) patients are infected with drug-resistant Mycobacterium tuberculosis strains (1).
While it is important to note that most teens do not abuse prescription drugs, the current level of abuse of certain prescription drugs concerns NIDA scientists.
Many of us now demand drugs not only for serious illnesses, but also for everything from allergies to toenail fungus.
The potential risks posed by the manufacture of drugs are not addressed, nor does the guidance apply to "orphan" drugs used only to treat rare diseases.
Statins are not the only class of safe drugs still under lock and key.
Many of these drugs had to be taken 3 times a day, making adherence especially challenging for many people.
Nevirapine, which manufacturer Boehringer Ingelheim markets as Viramune, is cheaper than the more effective drugs and is sometimes provided free of charge.