drug-related neuropathy

drug-related neuropathy

Neuropathy secondary to drugs Neurology A condition characterized by a loss of sensation and/or movement due to an agent that damages peripheral nerve axons, blocking neural conduction; DRNs often begin as a distal polyneuropathy and progress proximally Agents Amiodarone, hydralazine, perhexiline, vincristine, cisplatin, metronidazole, nitrofurantoin, thalidomide, INH, dapsone, phenytoin, disulfiram
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The patient had complained of numbness and tingling in her hands and feet before she was hospitalized, indicating that the drug-related neuropathy had existed before admission to the regional facility.
Drug-related neuropathy usually resolves when stavudine is promptly discontinued, although the symptoms may worsen temporarily when the drug is stopped.