drug holiday


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drug hol·i·day

(drŭg hol'i-dā),
Interval of time when a chronically medicated patient temporarily stops taking the medication; used to allow some recuperation of normal functions, to maintain sensitivity to the drug, and to reduce the likelihood of side-effects.
Farlex Partner Medical Dictionary © Farlex 2012

drug holiday

n.
A usually brief period during which a drug that is typically taken on a daily basis, such as an antidepressant, is not taken or is replaced with another in order to minimize certain side effects.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
Therapeutics A time frame during which a drug is proscribed, to evaluate baseline behaviour or decreased the dose of psychoactive drugs, and possibly the incidence of tardive dyskinesia
Vox populi A trip to a place where some usually illicit drugs are legal—e.g., Amsterdam, Jamaica
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

drug holiday

Psychiatry A period in which a prescribed drug is proscribed, to evaluate baseline behavior or ↓ the dose of psychoactive drugs, and possibly incidence of tardive dyskinesia. See Tardive dyskinesia.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

drug hol·i·day

(drŭg hol'i-dā)
Interval when a patient on long-term medication temporarily stops taking the prescribed medication; used to allow some recuperation of normal functions or to maintain sensitivity to the drug(s).
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

drug hol·i·day

(drŭg hol'i-dā)
Interval of time when a patient on long-term medication temporarily stops taking the medication; used to allow some recuperation of normal functions.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
"Drug holidays [from a bisphosphonate] have become increasingly common" because of concerns about potential adverse effects from prolonged, continuous bisphosphonate treatment, especially the risk for osteonecrosis of the jaw and atypical femoral fractures, he said.
Brittany Bindon, M.D., from the University of Chicago, and colleagues conducted a retrospective chart review of 401 patients with osteopenia or osteoporosis who began a BP drug holiday from 2004 to 2013.
Objective: To evaluate the oncologists thoughts about the positive and adverse effects of bisphosphonates, drug holiday and the awareness about BRONJ.
The symptoms often improve with a drug holiday, for instance during vacation.
That's why the recommendation is that around the 5-year point you can consider having a drug holiday or switching off the bisphosphonates.
Other times, patients can take a drug holiday, then restart the same statin without developing side effects.
Nevertheless, to reduce the risk of this side effect, many experts now recommend a "drug holiday" for appropriate patients on bisphosphonates, essentially giving them a break from the medication.
Pourhassan added that treatment substitution study has the potential to provide a drug holiday to patients from their daily pill regimen.
Studies have found adaptation rates generally are low (~10%) Pharmacologic Drug holiday May be an option for patients taking antidepressants with shorter half-lives and patients taking lower doses.
The IMA910 trial enrolled 92 patients with advanced CRC who had shown no progression following 12 weeks of first line oxaliplatin-based chemotherapy and who had decided to take a 'drug holiday' from their chemotherapy regimen.