drug allergy


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drug al·ler·gy

sensitivity (hypersensitivity) to a drug or other chemical.

drug allergy

hypersensitivity to a pharmacological agent. Manifestions range from a mild rash to anaphylactic shock, depending on the dose, and the allergen sensitivity of the individual. The primary drug that produces allergy is penicillin. Others include aspirin, phenylbutazone, novobiocin, other antibiotics, and radiopaque contrast media containing iodine. See also anaphylactic shock.

drug allergy

An immune response to a therapeutic. See Allergy.

drug al·ler·gy

(drŭg alĕr-jē)
Sensitivity (hypersensitivity) to a drug or other chemical.

allergy

an altered reactivity following second or subsequent exposure to antigen (allergen). See also hypersensitivity, allergic.

atopic allergy
hereditary predisposition to develop certain allergies. See atopy.
bacterial allergy
a specific hypersensitivity to a particular bacterial antigen, e.g. Mycobacterium tuberculosis; it is dependent on previous infection with the specific organism.
bronchial allergy
asthma.
cold allergy
a condition manifested by local and systemic reactions, mediated by histamine, which is released from mast cells and basophils as a result of exposure to cold.
delayed allergy
see delayed hypersensitivity.
drug allergy
see drug allergy.
drying-off allergy
see milk allergy (below).
food allergy
called also gastrointestinal allergy; see food hypersensitivity.
gastrointestinal allergy
see food allergy (above).
hereditary allergy
an allergy with a hereditary predisposition. The tendency to develop some forms of allergy is inherited, but the specific clinical form is not. IgE, formerly called reagin or reaginic antibody, may be involved. See also atopy.
induced allergy
allergy resulting from the injection of an antigen, contact with an antigen, or infection with a microorganism, as contrasted with hereditary allergy.
inhaled allergy
see atopy.
milk allergy
a hypersensitivity to the milk protein, α-casein. Signs, varying from urticaria to anaphylaxis, have occurred in Jersey cows when milk escapes from the udder into the bloodstream during the drying off period.
physical allergy
a condition in which physical agents, such as heat, cold or light, trigger an allergic response.

drug

1. any medicinal substance.
2. a narcotic.
3. to administer a drug.

drug administration
includes aerosol, oral, transtracheal infusion, subcutaneous, intramuscular, intravenous, intrauterine, intraperitoneal, intra-articular, intramammary, intrathecal, subconjunctival, percutaneous, percutaneous intraruminal, gas inhalation. Mass medication is per feed or drinking water or, in the case of captive fish, in the tank water. For feral animals individual dosing by projectile dart is usual, for group therapy administration by bait is possible.
drug allergy
immune-mediated hypersensitivity to a drug molecule. Includes anaphylaxis, cutaneous reaction.
animal drug
a drug specifically tested for, and recommended for use in, animals. A legal point of importance if an animal dies as a result of an unusual or allergic reaction to medication with a drug not licensed for use in animals.
drug augmented swine dysentery
pigs receiving prophylactic medication are more severely affected than untreated pigs.
bactericidal/bacteriostatic drug
drug binding
binding of a drug to a large molecule in the tissues or fluids, e.g. binding to protein in the blood, may affect the metabolism of the drug, especially its rate of excretion.
chemotherapeutic drug
drug combinations
a pharmaceutical strategy of combining several drugs into one formulation to provide for a specific requirement, e.g. an antibiotic combined with an anti-inflammatory agent in a mastitis ointment. Has the disadvantage that the dose of one drug is determined by the dose of the other.
controlled drug
availability and use of the drug is controlled by law. The control is at various levels of severity depending on the degree of danger associated with the uncontrolled use of each drug.
drug delayed swine dysentery
swine dysentery appears several days after treatment is discontinued.
drug delayed-augmented swine dysentery
after successful treatment during an attack of swine dysentery a more severe form of the disease occurs after treatment ceases.
drug diminished swine dysentery
the disease is reduced in severity as a result of treatment but is not eliminated.
drug eruption
an eruption or solitary skin lesion caused by a drug. See also dermatitis medicamentosa.
drug hypersensitivity
see drug allergy (above).
mutagenic d's
those that affect the DNA of the target organism have the hazard of creating new races of microorganisms with increased pathogenicity.
drug residue
the amount of the drug that can be detected in tissues at specified times after administration of the drug ceases. See also drug tolerance (below).
drug resistance
said mainly of antibacterial drugs and of microorganisms that are unaffected by the drug whilst most organisms of its species are susceptible. The resistance may be inherent or secondary to frequent exposure at sublethal levels. Resistance of an animal to a specific drug, e.g. to insulin, can also occur in this way.
drug resistant swine dysentery
medication of the feed is not an effective procedure and diarrhea and deaths occur.
drug safety margin
the magnitude of the difference between the dose required to produce a maximum therapeutic effect and that which produces a toxic effect. Registering authorities require this information.
drug selectivity
capacity to produce a single effect.
teratogenic drug
produces a toxic effect on the fetus at a particular phase of development producing a malformation.

Patient discussion about drug allergy

Q. I am worried about the allergic reactions I had from the Chinese herbal drug. I am worried about the allergic reactions I had from the Chinese herbal drug that I took for my arthritis…..are these safe?

A. Many people have some type of reaction to either a drug and even a supplement. You can check with your doc to get tested to see what your sensitivities are. Regarding arthritis, no milk, cheese, yogurt, butter, anything with milk for starters, AVOID like the plague! Suagr consumption too will raise hell with it. There is a product that someone I knew took, called, "Cell Guard" which he bought at a health food store or Whole Foods. After a couple of months, he was pain free. Its worth a try! Cell Guard is made with SOD or "superoxide dismutase"
Studies have shown that SOD can play a critical role in reducing internal inflammation and lessening pain associated with conditions such as arthritis! Check it out! Let me know how you do!

More discussions about drug allergy
References in periodicals archive ?
He explained that in most cases, a drug allergy develops when the immune system has become sensitive to the drug.
Various risk factors documented for developing multiple drug allergy are female sex, allergy to NSAID, human immunodeficiency virus infection, systemic lupus erythematosus and history of a severe drug reaction, especially DRESS.
We could not perform skin tests to confirm drug allergy to efavirenz because of logistical reasons [several readings in the case of epicutaneous tests (24 h, 48 h and 72 h)].
For a number of reasons, doctors frequently override drug allergy (and drug-drug interaction) alerts.
Correctly making a drug allergy diagnosis is further complicated if the drug must undergo some bioactive transformation before it can be immunogenic and stimulate the immune system.
Parental-reported drug allergy in 6-to 9-yrold urban school children.
Specifically, pharmacy and drug allergy data on about 18,300 patients who receive care from both departments are exchanged at the highest level of interoperability--that is, in computable form; at this level, the data are in a standardized format that a computer application can act on (for example, to provide alerts to clinicians of drug allergies).
One study, to be discussed today at the British Pharmaceutical Conference in Manchester, looked at the quality of drug allergy recording and use of wristbands on inpatient wards at the Queen Elizabeth Hospital in Gateshead.
WASHINGTON -- Clinicians ignored more than half of drug allergy warnings generated by computerized physician order entry programs, based on a review of nearly 30,000 medication orders for 2,732 hospitalized patients.
Without the availability of a penicillin skin test, physicians have "stepped back 30 years" in managing the 10% of the population who have a history of penicillin allergy, which is the most frequently reported drug allergy, said Eric Macy, M.

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