This leads to a decreased heart rate (negative chronotropic effect) and slowed AV-node conduction (negative dromotropic
effect) (Ehle et al., 2011).
The positive inotropic, dromotropic, and chronotropic heart rate are also increased by TH .
Adenosine also decreases [O.sub.2] demand by reducing the heart rate (a negative chronotropic effect), atrioventricular conduction (a negative dromotropic effect), and contractile force (a negative inotropic effect).
Methoxyflurane Anesthesia Augments The Chronotropic And Dromotropic
Effects of Verapamil.
When only chronotropic and dromotropic
effects are used as markers, the effects of fibers projecting on to atrial tissue remote from the sinus node or the AV node may be overlooked.
This combination new protocol provides the opportunity to improve image quality and reduce the negative chronotropic and dromotropic
effects of adenosine.
Both produce negative chronotropic, negative bathmotropic and negative dromotropic
effect on the heart.
The established positive inotropic and dromotropic effects were most distinctive for OA and MM.
The evaluation of inotropic and dromotropic effects and lengthening of the action potential duration was based on the computer analyses of ECG.
The positive inotropic and dromotropic effects are presented in Table 3, with OA and UA having the highest activity at the medium dose of 40 mg/kg.